Fmoc-Ala-OPfp
Fmoc-Ala-OPfp (CAS 86060-86-8), with the molecular formula C24H16F5NO4 and a molecular weight of 477.38 g/mol, is a derivative of the amino acid alanine. This compound is recognised for its utility in peptide synthesis, specifically as an activated amino acid ester. Its structure facilitates the formation of peptide bonds under controlled conditions, making it a valuable reagent in biochemical research and the development of peptide-based therapeutics.
- IUPAC
- Fmoc-L-alanine pentafluorophenyl ester

Peptide Synthesis
Fmoc-Ala-OPfp serves as a crucial building block in solid-phase and solution-phase peptide synthesis. The pentafluorophenyl ester provides good leaving group characteristics, enabling efficient coupling with amine groups of peptides.
Biochemical Research
This reagent is employed in various biochemical studies requiring the incorporation of alanine into peptide sequences. It is valuable for creating modified peptides for research into protein structure and function.
Drug Discovery and Development
In the pharmaceutical sector, Fmoc-Ala-OPfp is utilized in the synthesis of peptide mimetics and novel peptide-based drug candidates. Its use supports the advancement of therapeutic agents targeting a range of diseases.
| Molecular weight | 477.38 |
|---|---|
| Empirical formula | C24H16F5NO4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Ala-OPfp used for?
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Fmoc-Ala-OPfp is primarily used as an activated amino acid ester for peptide synthesis, facilitating the incorporation of alanine into peptide chains in both solid-phase and solution-phase methodologies. It is also utilized in biochemical research and the development of peptide-based therapeutics.
What is the CAS number and chemical formula for Fmoc-Ala-OPfp?
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The CAS number for Fmoc-Ala-OPfp is 86060-86-8, and its chemical formula is C24H16F5NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Ala-OPfp?
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Tech Serve Solutions supplies Fmoc-Ala-OPfp with an assay of ≥96.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should Fmoc-Ala-OPfp be handled and stored?
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Fmoc-Ala-OPfp should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be required. It should be stored at 2-8°C.
Is Fmoc-Ala-OPfp a controlled substance?
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Based on the provided data, Fmoc-Ala-OPfp (CAS 86060-86-8) is not indicated as a controlled substance.
How is Fmoc-Ala-OPfp shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-Ala-OPfp. Shipping and export procedures comply with all relevant regulations.
How can I request a sample or quote for Fmoc-Ala-OPfp?
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To request a sample or quote for Fmoc-Ala-OPfp, please contact the Tech Serve Solutions sales team through our official website or designated contact channels.
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