Fmoc-Arg(Pbf)-OH
Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine (CAS: 154445-77-9), a derivative of L-arginine, is a critical building block in solid-phase peptide synthesis. With the empirical formula C34H40N4O7S and a molecular weight of 648.77 g/mol, this compound facilitates the incorporation of arginine into peptide chains while protecting its side chain. It is essential for creating peptides with specific biological functions and therapeutic potential.
- IUPAC
- Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine,Nα-Fmoc-Nω-Pbf-L-arginine
- Synonyms
- Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginineNα-Fmoc-Nω-Pbf-L-arginine
Peptide Synthesis
Serves as a protected amino acid derivative for the synthesis of complex peptides, particularly those requiring arginine. The Fmoc and Pbf protecting groups ensure controlled coupling reactions in solid-phase synthesis.
Pharmaceutical Research
Used in the development of novel peptide-based therapeutics and drug candidates. Its specific structure is crucial for constructing peptides with desired pharmacological activities.
Chemical Biology
Employed in creating peptides for studying biological processes and protein interactions. Facilitates the design and synthesis of peptides for biochemical assays and research.
| Molecular weight | 648.77 |
|---|---|
| Empirical formula | C34H40N4O7S |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Arg(Pbf)-OH used for?
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Fmoc-Arg(Pbf)-OH is primarily used as a protected building block in solid-phase peptide synthesis to incorporate the amino acid arginine into peptide chains, essential for creating peptides with specific biological activities and for pharmaceutical research.
What are the CAS number and formula for Fmoc-Arg(Pbf)-OH?
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The CAS number for Fmoc-Arg(Pbf)-OH is 154445-77-9, and its empirical formula is C34H40N4O7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Arg(Pbf)-OH for research and chemical synthesis purposes. The specific assay and purity are detailed in the product's Certificate of Analysis; we do not represent this product as USP, BP, or EP grade.
How should Fmoc-Arg(Pbf)-OH be handled safely?
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Fmoc-Arg(Pbf)-OH is classified as a Warning substance due to hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, and gloves should be used. Handle in a well-ventilated area.
Is Fmoc-Arg(Pbf)-OH a controlled substance?
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Based on the provided data, Fmoc-Arg(Pbf)-OH is not listed as a controlled substance. However, users should always verify local regulations.
How is Fmoc-Arg(Pbf)-OH packed and shipped?
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Fmoc-Arg(Pbf)-OH is typically packed in appropriate containers for chemical stability and safety during transport. Tech Serve Solutions exports globally, adhering to international shipping regulations for chemical products.
How can I request a quote or sample of Fmoc-Arg(Pbf)-OH?
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To request a quote or a sample of Fmoc-Arg(Pbf)-OH, please contact the Tech Serve Solutions sales team via the website or listed contact information, specifying your requirements.
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