Fmoc-Asn-OH
Fmoc-Asn-OH (CAS: 71989-16-7) is an Fmoc-protected amino acid derivative with the molecular formula C19H18N2O5. This compound is a crucial building block in peptide synthesis, particularly for incorporating asparagine residues into peptide chains during solid-phase peptide synthesis (SPPS). Its use is essential in the fields of chemical biology and chemical synthesis for creating complex peptides and peptidomimetics.
- IUPAC
- Fmoc-L-asparagine
Peptide Synthesis
Fmoc-Asn-OH is widely employed as a protected amino acid in solid-phase peptide synthesis (SPPS). The Fmoc protecting group allows for facile deprotection under mild basic conditions, enabling controlled chain elongation.
Chemical Biology Research
This derivative is utilised in chemical biology to synthesise peptides with specific sequences for studying protein-ligand interactions, enzyme activity, and cellular signalling pathways.
Drug Discovery and Development
Fmoc-Asn-OH serves as a key intermediate in the synthesis of peptide-based therapeutics and drug candidates, contributing to advancements in pharmaceutical research.
Organic Synthesis
Beyond peptide chemistry, it can be incorporated into more complex organic molecules where an asparagine moiety is required, leveraging its specific chemical functionalities.
| Molecular weight | 354.36 |
|---|---|
| Empirical formula | C19H18N2O5 |
| Assay | ≥96.0% |
| Optical activity | [α]20/D −13±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | ~190 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Asn-OH used for?
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Fmoc-Asn-OH is primarily used as a protected building block in solid-phase peptide synthesis (SPPS) for the controlled incorporation of asparagine into peptide sequences. It is also valuable in chemical biology and general organic synthesis.
What is the CAS number and molecular formula for Fmoc-Asn-OH?
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The CAS number for Fmoc-Asn-OH is 71989-16-7, and its molecular formula is C19H18N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Asn-OH with an assay of ≥96.0%. TSS does not represent this product as USP, BP, or EP grade.
How should Fmoc-Asn-OH be handled and stored?
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Fmoc-Asn-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. It is recommended to store the compound at 2-8°C.
Is Fmoc-Asn-OH a controlled substance?
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The provided data does not indicate that Fmoc-Asn-OH is a controlled substance.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quote or sample of Fmoc-Asn-OH.
How is Fmoc-Asn-OH packed and shipped?
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Fmoc-Asn-OH is packed and exported according to industry best practices to ensure product integrity and safety during transit.
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