(R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide
(R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide (CAS: 75985-52-3) is a chiral organic compound with the formula C11H14N2O and a molecular weight of 190.24 g/mol. This aziridine derivative serves as a valuable building block in asymmetric synthesis. Its specific stereochemistry makes it useful in creating complex chiral molecules for research and development, particularly in the pharmaceutical and fine chemical sectors.
- IUPAC
- (R)-1-[(R)-α-methoxybenxyl]aziridine-2-carboxamide,1-(1′(R)-α-methylbenzyl)-aziridine-2(R)-carboxamide
![(R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide (C11H14N2O) — chemical structure, CAS 75985-52-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F75985-52-3.png&w=3840&q=75)
Asymmetric Synthesis
This compound is employed as a chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. It is valuable for introducing specific stereocenters into target compounds.
Organic Synthesis Intermediate
As an aziridine derivative, it acts as a versatile intermediate in various organic transformations. Its reactivity can be exploited for ring-opening reactions to form functionalized amines.
Pharmaceutical Research
The chiral nature of this molecule makes it a relevant starting material or intermediate for the synthesis of potential drug candidates and pharmaceutical agents where specific stereoisomerism is critical for biological activity.
Chemical Research and Development
It is utilised in academic and industrial research settings for the development of novel synthetic methodologies and the exploration of new chemical entities.
| Molecular weight | 190.24 |
|---|---|
| Empirical formula | C11H14N2O |
| Assay | 98% |
| Optical activity | [α]20/D +115°, c = 0.5% in methanol |
| Optical purity | ee: 98% (GLC) |
| Melting point | 111-114 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide used for?
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(R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis, particularly relevant for pharmaceutical research and chemical R&D.
What is the CAS number and formula for this compound?
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The CAS number is 75985-52-3 and the empirical formula is C11H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide with an assay of 98% and an optical purity of ee: 98%. This product is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide be handled?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation.
Is this compound a controlled substance?
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The provided data does not indicate that (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, can provide information on shipping and export for (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide upon request, adhering to all relevant regulations.
How can I request a sample or quote?
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To request a sample or a quote for (R)-1-[(1R)-α-Methylbenzyl]aziridine-2-carboxamide, please contact the Tech Serve Solutions sales team through our official channels.
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