(R)-1-[(SP)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine
(R)-1-[(SP)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine (CAS: 849924-76-1), with the formula C34H44FeP2 and molecular weight 570.51, is a highly effective chiral ferrocenyl phosphine ligand. It is widely employed in asymmetric synthesis, particularly in catalysing reactions where enantioselectivity is crucial. This advanced ligand is a key component in developing stereochemically pure compounds for pharmaceutical and fine chemical industries.
- IUPAC
- (1R)-1-[Bis(1,1-dimethylethyl)phosphino]-2-[(1R)-1-[bis(2-methylphenyl)phosphino]ethyl]ferrocene (acc to CAS),Josiphos SL-J505-1
![(R)-1-[(SP)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine (C34H44FeP2) — chemical structure, CAS 849924-76-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-76-1.png&w=3840&q=75)
Asymmetric Catalysis
This Josiphos-type ligand is instrumental in transition metal-catalysed asymmetric reactions. It facilitates high enantioselectivity in processes such as hydrogenation and C-C bond formation, vital for chiral drug synthesis.
Pharmaceutical Intermediate Synthesis
Its application is critical in the stereoselective synthesis of complex molecules that serve as intermediates for active pharmaceutical ingredients. The ligand's chiral nature ensures the production of desired enantiomers.
Fine Chemical Production
Used in the synthesis of high-value fine chemicals where specific stereochemistry is required, contributing to the development of advanced materials and specialty chemicals.
| Molecular weight | 570.51 |
|---|---|
| Empirical formula | C34H44FeP2 |
| Assay | 97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-[(SP)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical sectors.
What are the CAS number and chemical formula?
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The CAS number is 849924-76-1, and the chemical formula is C34H44FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 97% and an optical purity (ee) of ≥99%. It is supplied as a research or technical grade chemical, and is not represented as USP, BP, or EP grade.
What are the safety and handling considerations?
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This compound is classified under WGK 3 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling.
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring secure and compliant packaging suitable for international transport. Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team via the website or direct email, providing the product name and CAS number (849924-76-1).
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