VU0357121

CAS 433967-28-3C17H17F2NO2Biochemicals & Reagents

VU0357121 (CAS: 433967-28-3), a fluorinated benzamide derivative with the molecular formula C17H17F2NO2 and a molecular weight of 305.32 g/mol, is a potent and selective metabotropic glutamate receptor antagonist. Supplied as a powder with purity ≥98% (HPLC), it serves as a valuable tool in neuroscience research for investigating glutamatergic signalling pathways.

IUPAC: 4-Butoxy-N-(2,4-difluorophenyl)-benzamide,VU0357121

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VU0357121 (C17H17F2NO2) — chemical structure, CAS 433967-28-3; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyExcitatory Amino AcidsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesMetabotropic AgonistsNeuroscienceNeurotransmission

01 /Applications

Neuroscience Research

VU0357121 acts as a selective antagonist for specific metabotropic glutamate receptors (mGluRs), making it an essential reagent for studying the role of glutamatergic neurotransmission in neurological processes. Its application aids in understanding receptor function and developing therapeutic strategies for CNS disorders.

GPCR Signalling Studies

As a modulator of GPCRs, VU0357121 is utilised in biochemical assays and cell-based studies to probe G protein-coupled receptor signalling pathways. This facilitates research into receptor pharmacology and the identification of novel drug targets within the central nervous system.

Biochemical Assays

This compound is employed in various biochemical and cellular assays to investigate the intricate mechanisms of excitatory amino acid receptors. Its specificity allows researchers to dissect the functions of different receptor subtypes and their contribution to neuronal excitability.

02 /Properties

Molecular weight	305.32
Empirical formula	C17H17F2NO2
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: ≥18 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H410Very toxic to aquatic life with long-lasting effects

Precautionary statements

P273Avoid release to the environment
P501Dispose of contents and container per local regulations

Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	N
Risk statements (R)	50/53
Safety statements (S)	60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

433967-28-3

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is VU0357121 used for?

VU0357121 is primarily used in neuroscience research as a selective antagonist for metabotropic glutamate receptors (mGluRs) to study glutamatergic signalling pathways and their role in the central nervous system.

What are the CAS number and molecular formula for VU0357121?

The CAS number for VU0357121 is 433967-28-3, and its molecular formula is C17H17F2NO2.

What grade and purity does Tech Serve Solutions supply for VU0357121?

Tech Serve Solutions supplies VU0357121 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeial grade.

What are the safety and handling considerations for VU0357121?

VU0357121 is classified with GHS09 symbol and a 'Warning' signal word, indicating it is harmful to aquatic life with long-lasting effects (H410). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release into the environment. Consult the Safety Data Sheet for detailed handling and disposal information.

How is VU0357121 packed, shipped, and exported?

VU0357121 is typically supplied as a powder. For transportation, it is classified under UN 3077, Environmentally hazardous substance, solid, n.o.s. (VU0357121), Class 9, Packing Group III. Tech Serve Solutions ensures compliant packaging and global export.

How can I request a sample or a quote for VU0357121?

To request a sample or obtain a quote for VU0357121, please contact our sales team through the website or by phone, providing your contact details and intended use.