(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine palladium(II) dichloride
(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine palladium(II) dichloride (CAS: 854019-82-2; C32H52Cl2FeP2Pd) is a palladium catalyst complex featuring a Josiphos-type ferrocenyl diphosphine ligand. Its chiral nature makes it particularly valuable for asymmetric synthesis, enabling the enantioselective formation of chiral molecules. This complex is widely employed in catalysis for challenging organic transformations requiring high stereochemical control.
- IUPAC
- (SP-4-3)-[(2R)-1-[(1R)-1-[Bis(1,1-dimethylethyl)phosphino-P]ethyl]-2-(dicyclohexylphosphino-P)ferrocene]dichloropalladium (acc to CAS),Josiphos SK-K319-1a
![(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine palladium(II) dichloride (C32H52Cl2FeP2Pd) — chemical structure, CAS 854019-82-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F854019-82-2.png&w=3840&q=75)
Asymmetric Catalysis
This palladium complex serves as a crucial catalyst in asymmetric synthesis, facilitating the enantioselective creation of chiral intermediates and active pharmaceutical ingredients. Its efficacy is particularly noted in cross-coupling reactions.
Chiral Ligand Development
As a pre-catalyst or a source of a chiral diphosphine ligand, it is instrumental in developing new catalytic systems for stereoselective transformations. The Josiphos ligand framework offers tunable electronic and steric properties.
Pharmaceutical Intermediate Synthesis
The compound is employed in the synthesis of complex organic molecules, including those targeted for pharmaceutical applications where precise stereochemistry is paramount for biological activity.
| Molecular weight | 731.87 |
|---|---|
| Empirical formula | C32H52Cl2FeP2Pd |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine palladium(II) dichloride used for?
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This palladium complex is primarily used as a chiral catalyst in asymmetric synthesis, enabling the enantioselective formation of chiral compounds, particularly in cross-coupling reactions.
What are the CAS number and molecular formula?
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The CAS number is 854019-82-2, and the molecular formula is C32H52Cl2FeP2Pd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of ≥97% and an optical purity (ee) of ≥99%. It is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for this chemical?
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According to the safety data, this substance has a WGK (Germany) classification of 3, indicating it is hazardous to water. Appropriate handling procedures, including avoiding release into the environment, should be followed. Please consult the Safety Data Sheet (SDS) for comprehensive information.
How is this chemical packed and shipped?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring secure and compliant packaging for international shipment.
How can I request a sample or a quote?
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To request a sample or obtain a quotation, please contact the Tech Serve Solutions sales team directly through our website or by calling our customer service line.
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