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(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine

CAS 158923-09-2C36H44FeP2Chemical Synthesis

(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine (CAS 158923-09-2), a chiral ferrocenyl diphosphine ligand with the formula C36H44FeP2 and a molecular weight of 594.53 g/mol. This compound is a key component in asymmetric synthesis, enabling enantioselective transformations. It is widely recognised as a 'privileged ligand' due to its effectiveness in catalysing a broad range of challenging reactions, particularly in pharmaceutical intermediate production and fine chemical synthesis.

IUPAC
(1R)-1-(Dicyclohexylphosphino)-2-[(1R)-1-(diphenylphosphino)ethyl]ferrocene (acc to CAS),Josiphos SL-J004-1
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(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine (C36H44FeP2) — chemical structure, CAS 158923-09-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsJosiphos Ligands
01 /Applications

Asymmetric Catalysis

This ferrocenyl diphosphine ligand is extensively used in transition metal-catalysed asymmetric reactions, facilitating the synthesis of chiral molecules with high enantioselectivity. Its unique structure allows for efficient control over stereochemical outcomes.

Pharmaceutical Synthesis

It serves as a crucial ligand in the development of pharmaceutical intermediates, where precise control over chirality is paramount for drug efficacy and safety. Its application enables the production of complex chiral active pharmaceutical ingredients (APIs).

Fine Chemical Production

The ligand is instrumental in the synthesis of high-value fine chemicals, optimising catalytic processes for improved yields and enantiomeric excess. This contributes to more efficient and sustainable chemical manufacturing.

Research and Development

As a widely studied and versatile chiral catalyst component, it is a valuable reagent for academic and industrial research laboratories exploring new synthetic methodologies and catalytic systems.

02 /Properties
Molecular weight594.53
Empirical formulaC36H44FeP2
Assay≥97%
Optical purityee: ≥99%
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
158923-09-2
MDL number
MFCD00800280
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine used for?

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(R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine is primarily used as a chiral ligand in asymmetric synthesis, particularly in transition metal catalysis for producing enantiomerically enriched compounds for pharmaceuticals and fine chemicals.

What are the CAS number and formula for this compound?

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The CAS number is 158923-09-2, and the empirical formula is C36H44FeP2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of ≥97% and optical purity (ee) of ≥99%. It is provided as a research-grade chemical and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.

What are the safety and handling considerations?

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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating it is hazardous to water.

How is this chemical typically packed, shipped, and exported?

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Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all relevant regulations to ensure safe and compliant delivery to your laboratory or facility.

How can I request a quote or sample?

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Please contact our sales team via the website to request a detailed quotation or to inquire about obtaining a sample for your research needs.

Need (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenylethyl]diphenylphosphine in a specific grade or volume?