Amyloid β-Protein Fragment 25-35
Amyloid β-Protein Fragment 25-35 (CAS: 131602-53-4) is a synthetic peptide fragment of the amyloid precursor protein, with the empirical formula C45H81N13O14S and a molecular weight of 1060.27 g/mol. This fragment is widely used in research to study the mechanisms of Alzheimer's disease and other neurodegenerative conditions. It is recognised for its ability to induce neurotoxicity and mimic key pathological features of amyloidogenic diseases in cellular and animal models.
Neurodegenerative Disease Research
Amyloid β-Protein Fragment 25-35 is utilised as a research tool to investigate the pathogenesis of Alzheimer's disease and other neurodegenerative disorders. It serves as a model peptide for studying amyloid aggregation and neurotoxicity.
Cell Biology Studies
This peptide fragment is employed in cell-based assays to examine cellular responses to amyloid beta peptide, including mechanisms of apoptosis, oxidative stress, and inflammatory pathways.
Neuroscience Investigations
Researchers use this fragment to explore the role of amyloid beta in neuronal function, synaptic plasticity, and neuronal cell death, contributing to a deeper understanding of brain health and disease.
Drug Discovery and Screening
The fragment can be used in screening assays to identify potential therapeutic compounds that may inhibit amyloid beta aggregation or mitigate its neurotoxic effects.
| Molecular weight | 1060.27 |
|---|---|
| Empirical formula | C45H81N13O14S |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Composition | Protein Content, ≥80% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... APP(351) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Amyloid β-Protein Fragment 25-35 used for?
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Amyloid β-Protein Fragment 25-35 is primarily used in research settings to study Alzheimer's disease and other neurodegenerative conditions, investigate cellular mechanisms of neurotoxicity, and screen for potential therapeutic agents.
What are the CAS number and formula for Amyloid β-Protein Fragment 25-35?
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The CAS number for Amyloid β-Protein Fragment 25-35 is 131602-53-4, and its empirical formula is C45H81N13O14S.
What grade and purity does Tech Serve Solutions supply for Amyloid β-Protein Fragment 25-35?
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Tech Serve Solutions supplies Amyloid β-Protein Fragment 25-35 with an assay of ≥97% as determined by HPLC. This product is intended for research use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety precautions for handling Amyloid β-Protein Fragment 25-35?
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When handling this compound, it is essential to use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany classification of 3, indicating it is hazardous to water.
How is Amyloid β-Protein Fragment 25-35 packed, shipped, and exported?
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Amyloid β-Protein Fragment 25-35 is typically stored at −20°C. Tech Serve Solutions, as a global supplier, ensures compliant packing, shipping, and export procedures for research chemicals.
How can I request a sample or quote for Amyloid β-Protein Fragment 25-35?
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To request a sample or a quote for Amyloid β-Protein Fragment 25-35, please contact our sales team through the website or by phone, providing the product name and CAS number.
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