Vincristine sulfate
Vincristine sulfate (CAS: 2068-78-2) is a complex organic compound with the molecular formula C46H56N4O10 · H2SO4 and a molecular weight of 923.04 g/mol. This alkaloid is primarily utilised in scientific research for its antineoplastic properties, playing a role in cancer studies, and for its ability to inhibit cell cycle progression at the M-phase and monoamine oxidase (MAO).
- IUPAC
- 22-Oxovincaleukoblastine sulfate salt,Leurocristine sulfate salt,VCR,Vincristine sulfate salt
- Synonyms
- 22-Oxovincaleukoblastine sulfate saltLeurocristine sulfate saltVCRVincristine sulfate salt
Cancer Research
Vincristine sulfate is extensively employed in research settings to investigate various types of cancer and the mechanisms of anti-cancer drug action.
Cell Cycle Studies
Its capacity to arrest the cell cycle at the M-phase makes it a valuable tool for researchers studying cell division and related processes.
Drug Resistance Investigations
This compound is used in studies focused on understanding and overcoming multi-drug resistance in cancer cells.
Enzyme Inhibition Studies
Vincristine sulfate serves as an inhibitor of monoamine oxidase (MAO), facilitating research into enzyme activity and regulation.
| Molecular weight | 923.04 |
|---|---|
| Empirical formula | C46H56N4O10 · H2SO4 |
| Assay | 95.0-105.0% (HPLC) |
| Solubility | methanol: soluble20 mg/mL |
| Storage temperature | −20°C |
| Impurities tested | ≤12% ethanol(actual content given on label) |
| Application | Widely used in cancer research. In studies on multi-drug resistance. Used to inhibit cell cycle progression at M-phase. Used to inhibit monoamine oxidase (MAO). |
| Suitability | meets USP testing specifications |
Hazard statements
- H300Fatal if swallowed
- H341Suspected of causing genetic defects
- H361FD
Precautionary statements
- P264Wash thoroughly after handling
- P281Use personal protective equipment as required
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 63-25-62-68 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Vincristine sulfate used for?
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Vincristine sulfate is used in research for its antineoplastic properties, investigating cancer, cell cycle progression, and monoamine oxidase inhibition.
What is the CAS number and formula for Vincristine sulfate?
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The CAS number is 2068-78-2 and the formula is C46H56N4O10 · H2SO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Vincristine sulfate with an assay of 95.0-105.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with Vincristine sulfate?
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Vincristine sulfate is a dangerous substance, indicated by GHS06 and GHS08 symbols, with a 'Danger' signal word. It carries hazard statements H300 (Fatal if swallowed), H341 (Suspected of causing genetic defects), and H361fd (Suspected of damaging fertility. Suspected of damaging the unborn child).
How is Vincristine sulfate packed, shipped, and exported?
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Vincristine sulfate is shipped according to UN 2811 6.1 / PGII regulations. Please contact us for specific export details.
How can I request a sample or a quote for Vincristine sulfate?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team.
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