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Vinblastine sulfate salt

CAS 143-67-9C46H58N4O9 · H2SO4Biochemicals & Reagents

Vinblastine sulfate salt (CAS: 143-67-9), with the molecular formula C46H58N4O9 · H2SO4 and a molecular weight of 909.05 g/mol, is a white powder. This alkaloid is recognised for its antineoplastic properties, playing a crucial role in chemotherapy. It functions by disrupting microtubule formation, thereby inhibiting cell division in rapidly proliferating cancer cells. It is utilised in various cancer treatment regimens.

IUPAC
VLB,Vincaleukoblastine sulfate salt
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Vinblastine sulfate salt (C46H58N4O9 · H2SO4) — chemical structure, CAS 143-67-9; Life Science, fine chemical supplied by Tech Serve Solutions
AntibacterialAntibioticsAntibiotics A to ZAntibiotics T-ZAntibiotics by ApplicationAntitumor AgentsApplication IndexBioactive Small MoleculesBiochemicals and ReagentsCancer Research
01 /Applications

Oncology Research

Vinblastine sulfate salt is widely used in cancer research laboratories to investigate mechanisms of cell proliferation and to develop new anti-cancer therapeutic strategies. Its known antineoplastic effects make it a valuable tool for studying cellular processes affected by chemotherapy.

Chemotherapeutic Agent

As an antineoplastic antibiotic, vinblastine sulfate salt is a key component in the treatment of various cancers, including lymphomas, testicular cancer, and Kaposi's sarcoma. It is administered under strict medical supervision as part of established chemotherapy protocols.

Cell Biology Studies

This compound serves as a research reagent in cell biology to explore the dynamics of microtubules and their role in mitosis. Researchers utilize vinblastine sulfate salt to understand the effects of antimitotic agents on cell division and cellular architecture.

02 /Properties
Molecular weight909.05
Empirical formulaC46H58N4O9 · H2SO4
Assay≥96% (HPLC)
Formpowder
Colourwhite
SolubilityH2O: soluble10 mg/mLDMSO: soluble50 mg/mL
Storage temperature2-8°C
Melting point267 °C (dec.)(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-37/38-41
Safety statements (S)26-36/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
143-67-9
MDL number
MFCD00082457
Beilstein registry
3659812
05 /Additional specifications
Gene Informationhuman ... TBCC(6903)
AbsorptionA1mM/214 nm, ethanol 53.7A1mM/259 nm, ethanol 16.2A1mM/270 nm, 0.1 M phosphate buffer 14
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Vinblastine sulfate salt used for?

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Vinblastine sulfate salt is primarily used as an antineoplastic agent in chemotherapy for treating various cancers and as a research tool in oncology and cell biology studies.

What are the CAS number and formula for Vinblastine sulfate salt?

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The CAS number is 143-67-9, and the formula is C46H58N4O9 · H2SO4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Vinblastine sulfate salt with a purity of ≥96% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for handling Vinblastine sulfate salt?

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Vinblastine sulfate salt is dangerous. It is harmful if swallowed, causes skin irritation, serious eye damage, and may cause respiratory irritation (H302-H315-H318-H335). Always handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area, and avoid dust formation. Consult the Safety Data Sheet (SDS) for comprehensive information.

How is Vinblastine sulfate salt packed, shipped, and exported?

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Vinblastine sulfate salt is typically packed in secure containers suitable for fine chemicals and exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations for hazardous materials.

How can I request a sample or quote for Vinblastine sulfate salt?

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To request a sample or a quote for Vinblastine sulfate salt, please contact our sales department through the provided contact information on the Tech Serve Solutions website, specifying the product CAS number and required quantity.

Need Vinblastine sulfate salt in a specific grade or volume?