Ivabradine hydrochloride
Ivabradine hydrochloride (CAS: 148849-67-6), with the empirical formula C27H36N2O5 · HCl and a molecular weight of 505.05 g/mol, is a white to beige powder. This compound is primarily utilised in cell biology research, specifically within cell signaling, neuroscience, and the study of ion channels, including voltage-gated and monovalent potassium channels. It serves as a valuable tool for investigating cellular electrophysiology and related biological processes.
- IUPAC
- 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride

Ion Channel Research
Ivabradine hydrochloride is a selective inhibitor of the cardiac If current, making it a crucial reagent for studying the function and modulation of ion channels in cellular electrophysiology research. Its application extends to understanding the role of these channels in various physiological and pathological conditions.
Cell Signaling and Neuroscience Studies
This compound is employed in research focused on cell signaling pathways and neuronal function. Its ability to modulate ion channel activity provides insights into neurotransmission and other complex cellular communication mechanisms relevant to neuroscience.
Potassium Channel Modulation
As a modulator of potassium channels, Ivabradine hydrochloride aids in the investigation of potassium channel subtypes and their impact on cell excitability and function. This is particularly relevant for understanding cardiac and neuronal electrophysiology.
| Molecular weight | 505.05 |
|---|---|
| Empirical formula | C27H36N2O5 · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥5 mg/mL (warmed) |
| Optical activity | [α]/D +5 to +9°, c = 1 in DMSO |
| Storage temperature | 2-8°C |

Hazard statements
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ivabradine hydrochloride used for?
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Ivabradine hydrochloride is primarily used as a research chemical in cell biology, cell signaling, neuroscience, and ion channel studies, particularly focusing on voltage-gated and potassium channels.
What is the CAS number and formula for Ivabradine hydrochloride?
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The CAS number for Ivabradine hydrochloride is 148849-67-6, and its empirical formula is C27H36N2O5 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ivabradine hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Ivabradine hydrochloride be handled and stored?
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Ivabradine hydrochloride is classified under GHS09 with the signal word 'Warning' and hazard statement H400 ('Very toxic to aquatic life'). It should be stored desiccated at 2-8°C. Handle with appropriate personal protective equipment, and avoid release into the environment (P273).
Is Ivabradine hydrochloride a controlled substance?
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The provided data does not indicate that Ivabradine hydrochloride is a controlled substance.
How is Ivabradine hydrochloride packed and shipped?
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Ivabradine hydrochloride is shipped as UN 3077, Class 9, Packing Group III. Storage is recommended at 2-8°C in a desiccated state.
How can I request a sample or quote for Ivabradine hydrochloride?
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To request a sample or quote for Ivabradine hydrochloride, please contact our sales team through the website or via direct inquiry.
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