Istradefylline
Istradefylline (CAS: 155270-99-8), with the molecular formula C20H24N4O4 and a molecular weight of 384.43 g/mol, is a chemical compound supplied by Tech Serve Solutions. This white to beige powder serves as a selective antagonist for adenosine A2A receptors. It is primarily utilised in research settings for investigations into cell signaling, neuroscience, and neurotransmission, offering a valuable tool for understanding purinergic receptor functions.
- IUPAC
- (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione,KW-6002

Neuroscience Research
Istradefylline is employed in neuroscience research as a selective adenosine A2A receptor antagonist. It aids in studying the role of these receptors in neurotransmission and neurological pathways.
Cell Signaling Studies
Utilised in cell biology, this compound helps researchers investigate cell signaling cascades involving purinergic receptors. Its antagonist properties are key to dissecting these complex biological processes.
Pharmacological Tool
As a well-defined antagonist, Istradefylline is a valuable pharmacological tool for validating the function of adenosine A2A receptors in various experimental models.
| Molecular weight | 384.43 |
|---|---|
| Empirical formula | C20H24N4O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble5 mg/mL (clear solution) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Istradefylline used for?
+
Istradefylline is primarily used in neuroscience and cell biology research as a selective adenosine A2A receptor antagonist to study neurotransmission and cell signaling pathways.
What are the CAS number and formula for Istradefylline?
+
The CAS number for Istradefylline is 155270-99-8, and its empirical formula is C20H24N4O4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Istradefylline with an assay of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling Istradefylline?
+
Istradefylline is classified under GHS06 with the signal word 'Danger' and carries the hazard statement H301 (Toxic if swallowed). It should be handled with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is Istradefylline stored and shipped?
+
Istradefylline is typically stored at 2-8°C. It is packaged and shipped according to relevant regulations for hazardous materials, identified under UN 2811 6.1 / PGIII.
How can I request a quote or sample for Istradefylline?
+
To request a quote or a sample of Istradefylline, please contact our sales team via the website or direct email, providing your specific requirements.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis