Boc-(R)-α-(4-fluorobenzyl)-Pro-OH
Boc-(R)-α-(4-fluorobenzyl)-Pro-OH (CAS: 706806-64-6), with the molecular formula C17H22FNO4 and a molecular weight of 323.36 g/mol, is a key unnatural amino acid derivative. This protected proline analogue is valued for its utility in complex organic synthesis and chemical biology research. Its specific stereochemistry and functionalisation make it an important building block for creating novel peptides and peptidomimetics.
- IUPAC
- (R)-1-Boc-2-(4-fluorobenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-fluorobenzyl)-L-proline

Peptide Synthesis
Serves as a crucial unnatural amino acid building block for the construction of modified peptides and peptidomimetics. Its unique structure can introduce specific conformational constraints or functionalities into peptide chains.
Chemical Biology
Utilised in chemical biology research for developing probes or modified biomolecules. The fluorobenzyl group can potentially serve as a label or influence molecular interactions.
Organic Synthesis
A valuable intermediate in advanced organic synthesis, particularly for creating complex chiral molecules. Its Boc-protected nature facilitates controlled synthetic strategies.
Drug Discovery
Incorporated into the design of novel therapeutic agents or lead compounds. The unnatural amino acid structure can improve pharmacokinetic properties or target interactions.
| Molecular weight | 323.36 |
|---|---|
| Empirical formula | C17H22FNO4 |
| Assay | ≥98.0% (HPLC) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(R)-α-(4-fluorobenzyl)-Pro-OH used for?
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Boc-(R)-α-(4-fluorobenzyl)-Pro-OH is primarily used as a building block in peptide synthesis, chemical biology research, organic synthesis, and drug discovery.
What are the CAS number and formula for this compound?
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The CAS number is 706806-64-6 and the molecular formula is C17H22FNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-(R)-α-(4-fluorobenzyl)-Pro-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Boc-(R)-α-(4-fluorobenzyl)-Pro-OH be handled?
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This compound is classified as harmful if swallowed (H302). Handling requires appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including Boc-(R)-α-(4-fluorobenzyl)-Pro-OH.
How can I request a quote or sample?
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To request a quote or sample of Boc-(R)-α-(4-fluorobenzyl)-Pro-OH, please contact our sales team through the website or by phone.
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