Boc-(S)-3-thienylglycine
Boc-(S)-3-thienylglycine (CAS: 910309-12-5), with the molecular formula C11H15NO4S and a molecular weight of 257.31 g/mol, is a chiral building block used in organic synthesis. This protected amino acid derivative features a Boc protecting group on the amine and a thienyl moiety, making it valuable for constructing complex molecules. It is employed in asymmetric synthesis and peptide chemistry, contributing to the development of novel compounds.
- IUPAC
- (S)-2-[(tert-Butoxycarbonyl)amino]-2-(3-thienyl)acetic acid
Asymmetric Synthesis
Boc-(S)-3-thienylglycine serves as a crucial chiral building block in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex organic molecules, including pharmaceuticals and advanced materials.
Peptide Chemistry
As a modified amino acid derivative, it is utilised in peptide synthesis to introduce specific structural or functional elements. The Boc protection facilitates controlled coupling reactions in peptide chain elongation.
Chemical Biology and Drug Discovery
The compound's unique structure, incorporating a thiophene ring and a chiral centre, makes it a valuable intermediate in chemical biology research and drug discovery programmes aiming for novel therapeutic agents.
Heterocyclic Compound Synthesis
Boc-(S)-3-thienylglycine acts as a precursor for the synthesis of various heterocyclic compounds, particularly those containing a thienyl group, which are prevalent in medicinal chemistry.
| Molecular weight | 257.31 |
|---|---|
| Empirical formula | C11H15NO4S |
| Assay | ≥97.5% (HPLC)98% |
| Optical activity | [α]/D +111±5°, c = 1 in ethanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(S)-3-thienylglycine used for?
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Boc-(S)-3-thienylglycine is used in asymmetric synthesis, peptide chemistry, chemical biology, and the synthesis of heterocyclic compounds. It serves as a chiral building block for constructing complex organic molecules.
What is the CAS number and formula for Boc-(S)-3-thienylglycine?
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The CAS number for Boc-(S)-3-thienylglycine is 910309-12-5, and its empirical formula is C11H15NO4S.
What grade and purity does Tech Serve Solutions supply for Boc-(S)-3-thienylglycine?
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Tech Serve Solutions supplies Boc-(S)-3-thienylglycine with a purity of ≥97.5% (HPLC) or 98%. This is a research-grade chemical and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Boc-(S)-3-thienylglycine?
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When handling Boc-(S)-3-thienylglycine, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound has a WGK Germany classification of 3, indicating a high hazard.
How is Boc-(S)-3-thienylglycine shipped and exported by Tech Serve Solutions?
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Boc-(S)-3-thienylglycine is stored at 2-8°C. Tech Serve Solutions is a global supplier and exporter, equipped to handle the shipping and export of this chemical according to international regulations.
How can I request a quote or sample for Boc-(S)-3-thienylglycine?
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To request a quote or sample of Boc-(S)-3-thienylglycine, please contact the Tech Serve Solutions sales team through our website or by phone.
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