Boc-(R)-α-(4-tert-butylbenzyl)-Pro-OH

CAS 957310-66-6C21H31NO4Chemical Synthesis

Boc-(R)-α-(4-tert-butylbenzyl)-Pro-OH (CAS: 957310-66-6) is a chiral molecule with the formula C21H31NO4 and a molecular weight of 361.48 g/mol. This N-Boc protected unnatural amino acid derivative is primarily employed in chemical synthesis, particularly within peptide chemistry and the development of chemical biology tools. Its structure makes it a valuable building block for creating complex peptides and peptidomimetics with specific stereochemical properties.

IUPAC: (R)-1-Boc-2-(4-tert-butylbenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-tert-butylbenzyl)-L-proline

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Boc-(R)-α-(4-tert-butylbenzyl)-Pro-OH (C21H31NO4) — chemical structure, CAS 957310-66-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryProline Derivatives

01 /Applications

Peptide Synthesis

Serves as a non-proteinogenic amino acid building block for the synthesis of peptides and peptidomimetics. Its inclusion can introduce specific structural constraints or modify biological activity.

Chemical Biology Research

Utilised in the design and synthesis of modified peptides for probing biological systems or developing novel therapeutic agents. The tert-butylbenzyl side chain offers unique steric and hydrophobic characteristics.

Asymmetric Synthesis

Acts as a chiral precursor in the development of new synthetic methodologies and the construction of stereochemically defined molecules.

02 /Properties

Molecular weight	361.48
Empirical formula	C21H31NO4
Assay	≥97.0% (HPLC)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

957310-66-6

MDL number

MFCD06796822

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-(R)-α-(4-tert-butylbenzyl)-Pro-OH used for?

This compound is used as a building block in peptide synthesis, chemical biology research, and asymmetric synthesis due to its unnatural amino acid structure.

What are the CAS number and chemical formula for Boc-(R)-α-(4-tert-butylbenzyl)-Pro-OH?

The CAS number is 957310-66-6 and the chemical formula is C21H31NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with a purity of ≥97.0% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the primary safety hazards associated with this compound?

This compound is classified with GHS07 symbol and a Warning signal word. It carries the hazard statement H302 (Harmful if swallowed) and is classified as Xn with risk statement R22 in Europe. Appropriate personal protective equipment, including eyeshields and gloves, should be used.