4-Methoxy-2-methylphenyl isocyanate
4-Methoxy-2-methylphenyl isocyanate (CAS: 60385-06-0) is an organic compound with the formula CH3OC6H3(CH3)NCO and a molecular weight of 163.17 g/mol. It serves as a valuable building block in chemical synthesis. This isocyanate derivative is primarily utilised in organic chemistry for the creation of more complex molecules, acting as a reactive intermediate in various chemical transformations.

Organic Synthesis Intermediate
This compound is a key intermediate in the synthesis of diverse organic molecules. Its isocyanate functionality readily participates in addition reactions with nucleophiles.
Pharmaceutical Building Block
Used in the development of novel pharmaceutical agents, it can be incorporated into target molecules to impart specific chemical properties or functionalities.
Material Science Research
Applicable in research settings for the development of new polymers or functional materials where the isocyanate group can be leveraged for cross-linking or surface modification.
| Molecular weight | 163.17 |
|---|---|
| Linear formula | CH3OC6H3(CH3)NCO |
| Assay | 98% |
| Boiling point | 76 °C/1 mmHg(lit.) |
| Density | 1.121 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.546(lit.) |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxy-2-methylphenyl isocyanate used for?
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4-Methoxy-2-methylphenyl isocyanate is primarily used as a building block and intermediate in organic synthesis, including in pharmaceutical and material science research.
What is the CAS number and formula for 4-Methoxy-2-methylphenyl isocyanate?
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The CAS number is 60385-06-0 and the linear formula is CH3OC6H3(CH3)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxy-2-methylphenyl isocyanate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 4-Methoxy-2-methylphenyl isocyanate be handled safely?
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This compound presents hazards including skin, eye, and respiratory irritation, and potential sensitisation. Handle with appropriate personal protective equipment, including gloves, eye protection, and a respirator, in a well-ventilated area. It is classified with GHS07 and GHS08 symbols and a Danger signal word.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Methoxy-2-methylphenyl isocyanate.
How can I request a quote or sample?
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To request a quote or sample of 4-Methoxy-2-methylphenyl isocyanate, please contact our sales team via the website or by phone.
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