3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-1-decanethiol
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-1-decanethiol (CAS: 34143-74-3), with the linear formula CF3(CF2)7CH2CH2SH and a molecular weight of 480.18 g/mol, is a specialized fluorinated thiol. This compound finds utility in various chemical synthesis applications, particularly within fluorous chemistry, enabling the creation of Rf-tagged materials and scavengers for efficient solution-phase purification. Its unique properties lend themselves to advanced material science and organic synthesis.
- IUPAC
- 1H,1H,2H,2H-Perfluoro-1-decanethiol
- Synonyms
- 4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-1-decanethiol1H,1H,2H,2H-Perfluoro-1-decanethiol

Fluorous Synthesis
This compound is a key reagent in fluorous synthesis, facilitating the incorporation of perfluoroalkyl chains. It is used to create fluorous tags for reagents and intermediates, enabling facile separation and purification.
Rf-Tagged Scavengers
Its fluorous nature makes it suitable for preparing Rf-tagged scavengers. These can be employed in solid-phase or solution-phase synthesis to remove excess reagents or by-products by selective extraction into a fluorous phase.
Surface Modification
The thiol group allows for chemisorption onto noble metal surfaces, while the long fluorinated chain can impart unique surface properties such as hydrophobicity and oleophobicity.
Specialty Chemical Synthesis
Serves as a building block in the synthesis of specialized fluorinated organic compounds, contributing unique physicochemical characteristics to the final molecules.
| Molecular weight | 480.18 |
|---|---|
| Linear formula | CF3(CF2)7CH2CH2SH |
| Assay | ≥96.0% |
| Boiling point | 82 °C/12 mmHg |
| Density | 1.678 g/mL at 25 °C |
| Refractive index | n20/D 1.333 |
| Melting point | 15 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-1-decanethiol used for?
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This compound is primarily used in fluorous synthesis, for creating Rf-tagged solution-phase scavengers, and in specialty chemical synthesis where its fluorinated chain and thiol functionality are beneficial.
What is the CAS number and chemical formula for this product?
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The CAS number is 34143-74-3 and the linear formula is CF3(CF2)7CH2CH2SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥96.0%. We do not represent this product as USP, EP, BP, or any other pharmacopoeial grade.
What are the main hazards associated with this chemical?
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This compound is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment, such as eyeshields, gloves, and a suitable respirator, must be used during handling.
How is this chemical shipped and exported?
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As a specialist global supplier and exporter since 1998, Tech Serve Solutions handles the packaging and export of this chemical, adhering to all relevant regulations for international shipment.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please use the contact form on our website or contact our sales department directly with your specific requirements.
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