3,3,5,5-Tetramethyl-1-pyrroline N-oxide

CAS 10135-38-3C8H15NOChemical Synthesis

3,3,5,5-Tetramethyl-1-pyrroline N-oxide (CAS: 10135-38-3; C8H15NO) is a stable nitroxide radical and a valuable laboratory reagent with a molecular weight of 141.21 g/mol. Primarily utilised as a spin trapping agent in Electron Spin Resonance (ESR/EPR) spectroscopy, it plays a crucial role in detecting and characterising short-lived radical species. It is also employed as a building block in chemical synthesis and as an analytical reagent.

Synonyms: 5-Tetramethyl-1-pyrroline N-oxide10135-38-3C8H15NO

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3,3,5,5-Tetramethyl-1-pyrroline N-oxide (C8H15NO) — chemical structure, CAS 10135-38-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Analytical ReagentsAnalytical/ChromatographyBuilding BlocksChemical SynthesisHeterocyclic Building BlocksPyrrolinesSpectroscopy

01 /Applications

Spin Trapping Agent

3,3,5,5-Tetramethyl-1-pyrroline N-oxide serves as an effective spin trapping reagent in Electron Spin Resonance (ESR/EPR) spectroscopy. It reacts with transient free radicals to form more stable nitroxide radicals, which can then be detected and analysed.

Analytical Reagent

This compound functions as an analytical reagent, aiding in the identification and quantification of various substances through spectroscopic methods. Its specific properties make it suitable for certain chromatographic applications as well.

Chemical Synthesis Building Block

As a heterocyclic building block, 3,3,5,5-Tetramethyl-1-pyrroline N-oxide can be incorporated into more complex molecular structures. Its reactive nature allows for diverse synthetic transformations in organic chemistry.

02 /Properties

Molecular weight	141.21
Empirical formula	C8H15NO
Assay	95%
Boiling point	73 °C/1 mmHg(lit.)
Storage temperature	−20°C
Application	3,3,5,5-Tetramethyl-1-pyrroline N-oxide was used as a spin traping reagent1.
Melting point	58-61 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

10135-38-3

MDL number

MFCD00010542

PubChem substance

24854646

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,3,5,5-Tetramethyl-1-pyrroline N-oxide used for?

It is primarily used as a spin trapping agent in Electron Spin Resonance (ESR/EPR) spectroscopy to detect short-lived radical species. It also finds application as an analytical reagent and a building block in chemical synthesis.

What are the CAS number and formula for 3,3,5,5-Tetramethyl-1-pyrroline N-oxide?

The CAS number is 10135-38-3 and the empirical formula (Hill notation) is C8H15NO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3,3,5,5-Tetramethyl-1-pyrroline N-oxide with an assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling precautions for this chemical?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK Germany 3, indicating a high hazard.