4-Methoxy-2-methylphenylmagnesium bromide solution

CAS 148706-30-3CH3OC6H3(CH3)MgBrChemical Synthesis

4-Methoxy-2-methylphenylmagnesium bromide solution (CAS 148706-30-3) is an organometallic reagent with the linear formula CH3OC6H3(CH3)MgBr and a molecular weight of 225.37 g/mol. Supplied as a 0.5 M solution in THF, this Grignard reagent is a valuable intermediate in organic synthesis. It is primarily used for the introduction of the 4-methoxy-2-methylphenyl group into various organic molecules, facilitating the construction of complex structures.

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4-Methoxy-2-methylphenylmagnesium bromide solution (CH3OC6H3(CH3)MgBr) — chemical structure, CAS 148706-30-3; Chemistry, fine chemical supplied by Tech Serve Solutions

ArylChemical SynthesisGrignard ReagentsOrganometallic Reagents

01 /Applications

Carbon-Carbon Bond Formation

As a Grignard reagent, it readily reacts with electrophiles such as aldehydes, ketones, esters, and epoxides to form new carbon-carbon bonds. This is fundamental for building more complex molecular frameworks in pharmaceutical and fine chemical synthesis.

Synthesis of Substituted Aromatics

This reagent allows for the precise incorporation of the 4-methoxy-2-methylphenyl moiety into target molecules. It is particularly useful in the development of novel organic compounds with potential biological activity or specific material properties.

Intermediate for Pharmaceutical Research

The specific substitution pattern of this arylmagnesium bromide makes it a useful building block in the synthesis of drug candidates and intermediates, aiding in medicinal chemistry research and development.

02 /Properties

Molecular weight	225.37
Linear formula	CH3OC6H3(CH3)MgBr
Boiling point	65 °C
Density	0.956 g/mL at 25 °C
Concentration	0.5 M in THF
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H225Highly flammable liquid and vapour
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking
P261Avoid breathing dust, fume, gas or vapours
P281Use personal protective equipment as required
P305IF IN EYES

Transport (UN / ADR)	UN 2924 8(3) / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	F,Xn
Risk statements (R)	11-19-36/37-40
Safety statements (S)	16-26-36/37
Supplemental hazards	May form explosive peroxides.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

148706-30-3

MDL number

MFCD01319918

PubChem substance

24880018

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Methoxy-2-methylphenylmagnesium bromide solution used for?

This Grignard reagent is primarily used in organic synthesis for the formation of carbon-carbon bonds and the introduction of the 4-methoxy-2-methylphenyl group into organic molecules, serving as an intermediate in the synthesis of complex compounds and potential pharmaceutical agents.

What is the CAS number and formula for this compound?

The CAS number is 148706-30-3 and the linear formula is CH3OC6H3(CH3)MgBr.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent it as USP, BP, or EP grade.

How should 4-Methoxy-2-methylphenylmagnesium bromide solution be handled?

This is a flammable liquid and vapour (H225) and causes serious eye irritation (H319) and may cause respiratory irritation (H335). It is suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store at 2-8°C.

How is this product shipped and exported?

This product is classified under UN 2924, Hazard Class 8 (Corrosive), Subsidiary Hazard 3 (Flammable Liquid), Packing Group II. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.

How can I request a sample or quote?

To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (148706-30-3).