Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH
Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH (CAS: 957310-45-1) is a chiral building block with the molecular formula C18H22F3NO4 and a molecular weight of 373.37 g/mol. This unnatural amino acid derivative is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its specific stereochemistry and functional groups make it valuable for constructing complex molecules and studying biological processes.
- IUPAC
- (R)-1-Boc-2-(4-trifluoromethylbenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-trifluoromethylbenzyl)-L-proline

Peptide Synthesis
Serves as a specialised, unnatural amino acid building block in the synthesis of modified peptides. Its inclusion can introduce unique structural or functional properties into peptide sequences.
Chemical Synthesis Intermediate
A valuable intermediate for organic synthesis, enabling the construction of complex chiral molecules. The trifluoromethylbenzyl and Boc-protected proline moieties offer versatile reactivity.
Chemical Biology Research
Used in the development of probes or modified peptides for investigating biological pathways and protein interactions. The trifluoromethyl group can act as a useful label.
Drug Discovery
Contributes to the synthesis of novel chemical entities with potential therapeutic applications, leveraging its unique structural features for drug design.
| Molecular weight | 373.37 |
|---|---|
| Empirical formula | C18H22F3NO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH used for?
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Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH is used as a specialised building block in chemical synthesis, peptide chemistry, and chemical biology research to create modified peptides and complex chiral molecules.
What are the CAS number and formula for Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH?
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The CAS number is 957310-45-1 and the empirical formula is C18H22F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH with an assay of ≥98.0% determined by HPLC. This product is supplied for research and development purposes and is not guaranteed to be USP, BP, or EP grade.
How should Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH be handled safely?
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Safe handling requires the use of eyeshields and gloves. Personnel should be aware that this compound is classified with a WGK Germany of 3, indicating a significant hazard to water.
Can Tech Serve Solutions export Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH.
How can I request a sample or quote for Boc-(R)-α-(4-trifluoromethylbenzyl)-Pro-OH?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via the website or designated contact channels.
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