Boc-(R)-4-(2-propynyl)-L-proline
Boc-(R)-4-(2-propynyl)-L-proline (CAS: 959581-98-7) is a chiral building block with the molecular formula C13H19NO4 and a molecular weight of 253.29 g/mol. This Boc-protected unnatural amino acid derivative features a propargyl side chain, making it valuable in conjugation chemistry and asymmetric synthesis. It serves as a versatile intermediate in the development of novel pharmaceuticals and biochemical probes.
- IUPAC
- Boc-(R)-4-propargyl-L-proline
Asymmetric Synthesis
This chiral proline derivative is employed as a building block in enantioselective synthesis to construct complex molecules with defined stereochemistry. Its unique structure allows for the introduction of specific chiral centres in target compounds.
Peptide Chemistry
As an unnatural amino acid, it can be incorporated into peptide sequences to modify their structure and function. This is useful for developing peptide-based therapeutics or probes with enhanced stability or specific binding properties.
Conjugation Chemistry
The terminal alkyne on the propargyl group is suitable for click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). This enables the facile conjugation of the proline moiety to biomolecules, polymers, or surfaces.
Chemical Biology
Its incorporation into molecular scaffolds facilitates the study of biological processes. It can be used to create labelled compounds or probes for investigating protein-ligand interactions or enzyme activity.
| Molecular weight | 253.29 |
|---|---|
| Empirical formula | C13H19NO4 |
| Assay | ≥96%≥96.0% (TLC) |
| Optical activity | [α]/D -34.0±2°, c = 1% in ethanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(R)-4-(2-propynyl)-L-proline used for?
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Boc-(R)-4-(2-propynyl)-L-proline is primarily used as a chiral building block in asymmetric synthesis, for creating peptide modifications, in conjugation chemistry via click reactions, and as a tool in chemical biology research.
What is the CAS number and molecular formula for Boc-(R)-4-(2-propynyl)-L-proline?
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The CAS number is 959581-98-7, and its molecular formula is C13H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥96% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Boc-(R)-4-(2-propynyl)-L-proline be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at 2-8°C to maintain stability.
Is Boc-(R)-4-(2-propynyl)-L-proline a controlled substance?
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The provided data does not indicate that Boc-(R)-4-(2-propynyl)-L-proline is a controlled substance.
How can I request a sample or quote for Boc-(R)-4-(2-propynyl)-L-proline?
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Please contact our sales department through the website to request a sample or a formal quotation for Boc-(R)-4-(2-propynyl)-L-proline.
What are the shipping and export details for this chemical?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export documentation will be provided based on your location and order requirements.
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