Boc-(R)-3-thienylglycine
Boc-(R)-3-thienylglycine (CAS: 33130-97-1, C11H15NO4S) is a valuable chiral building block featuring a Boc-protected amine and a thiophene moiety. With a molecular weight of 257.31 g/mol, this compound serves as a key intermediate in asymmetric synthesis and peptide chemistry. Its (R)-configuration makes it particularly useful for constructing stereochemically defined molecules, finding applications in the development of pharmaceuticals and advanced materials.
- IUPAC
- (R)-2-[(tert-Butoxycarbonyl)amino]-2-(3-thienyl)acetic acid
Asymmetric Synthesis
Boc-(R)-3-thienylglycine is employed as a chiral synthon in the construction of complex organic molecules. Its defined stereochemistry is critical for creating enantiomerically pure compounds, often required in pharmaceutical research and development.
Peptide Chemistry
As a protected unnatural amino acid derivative, this compound is used in solid-phase or solution-phase peptide synthesis. It allows for the incorporation of a thienyl group into peptide sequences to modify their structure and biological activity.
Medicinal Chemistry
The thienyl ring offers unique electronic and steric properties, making Boc-(R)-3-thienylglycine a useful building block for designing novel drug candidates. It can be incorporated into biologically active molecules to explore structure-activity relationships.
Chemical Biology
This molecule can be utilised in the synthesis of probes or modified biomolecules for studying biological processes. Its incorporation into larger structures can help elucidate protein interactions or enzymatic mechanisms.
| Molecular weight | 257.31 |
|---|---|
| Empirical formula | C11H15NO4S |
| Assay | ≥97.5% (HPLC)98% |
| Optical activity | [α]/D -111±5°, c = 1 in ethanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(R)-3-thienylglycine used for?
+
Boc-(R)-3-thienylglycine is primarily used as a chiral building block in asymmetric synthesis, peptide chemistry, medicinal chemistry, and chemical biology research for the preparation of complex organic molecules and modified peptides.
What are the CAS number and molecular formula for Boc-(R)-3-thienylglycine?
+
The CAS number for Boc-(R)-3-thienylglycine is 33130-97-1, and its molecular formula is C11H15NO4S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Boc-(R)-3-thienylglycine with an assay of ≥97.5% (HPLC) or 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling requirements for Boc-(R)-3-thienylglycine?
+
When handling Boc-(R)-3-thienylglycine, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is Boc-(R)-3-thienylglycine shipped and exported?
+
Boc-(R)-3-thienylglycine is typically stored at 2-8°C. Tech Serve Solutions, a global supplier and exporter, can manage the logistics for exporting this chemical worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for Boc-(R)-3-thienylglycine?
+
To request a sample or a quotation for Boc-(R)-3-thienylglycine, please contact our sales department via the website or by phone. Our team will be pleased to assist you with your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis