Boc-(R)-2-thienylglycine
Boc-(R)-2-thienylglycine (CAS: 74562-03-1), with the molecular formula C11H15NO4S and a molecular weight of 257.31 g/mol, is a protected unnatural amino acid derivative. It serves as a valuable chiral building block in organic synthesis and peptide chemistry. This compound is particularly useful in the development of novel pharmaceuticals and in chemical biology research, enabling the introduction of thienylglycine moieties into complex molecular structures.
- IUPAC
- (R)-2-[(tert-Butoxycarbonyl)amino]-2-(2-thienyl)acetic acid
Chiral Synthesis
As a chiral building block, Boc-(R)-2-thienylglycine is employed in asymmetric synthesis to construct enantiomerically pure compounds. Its specific stereochemistry is crucial for developing stereoselective synthetic routes.
Peptide Chemistry
This protected amino acid derivative is incorporated into peptide chains to create peptidomimetics or peptides with modified properties. The Boc protecting group facilitates controlled peptide bond formation.
Pharmaceutical Intermediates
It functions as a key intermediate in the synthesis of various pharmaceutical agents. The thienyl group and chiral center are often integral to the biological activity of drug candidates.
Chemical Biology
Boc-(R)-2-thienylglycine can be used in chemical biology to probe biological pathways or to develop new diagnostic and therapeutic agents incorporating unnatural amino acid structures.
| Molecular weight | 257.31 |
|---|---|
| Empirical formula | C11H15NO4S |
| Assay | ≥96.5% (HPLC)97% |
| Optical activity | [α]/D -90±5°, c = 1 in ethanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(R)-2-thienylglycine used for?
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Boc-(R)-2-thienylglycine is used in asymmetric synthesis, peptide chemistry, as a pharmaceutical intermediate, and in chemical biology research as a chiral building block.
What are the CAS number and formula for Boc-(R)-2-thienylglycine?
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The CAS number is 74562-03-1 and the empirical formula is C11H15NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-(R)-2-thienylglycine with an assay of ≥96.5% (HPLC) and 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Boc-(R)-2-thienylglycine be handled and stored?
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Handle Boc-(R)-2-thienylglycine with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at 2-8°C.
Is Boc-(R)-2-thienylglycine a hazardous substance?
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According to WGK Germany, this compound is rated 3, indicating it is hazardous to water. Appropriate safety precautions must be taken during handling and disposal.
How is Boc-(R)-2-thienylglycine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and Boc-(R)-2-thienylglycine can be exported worldwide.
How can I request a sample or quote for Boc-(R)-2-thienylglycine?
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To request a sample or quote, please contact our sales team through the website or by phone.
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