Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH
Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH (CAS: 1217720-94-9) is a trifluoromethylbenzyl-substituted proline derivative with the molecular formula C18H22F3NO4. This unnatural amino acid derivative is primarily utilised in chemical synthesis and peptide chemistry. Its structure incorporates a Boc-protected amine and a chiral centre, making it a valuable building block for creating complex peptides and modified amino acid structures in research and development.
- IUPAC
- (S)-1-Boc-2-(4-trifluoromethylbenzyl)-2-pyrrolidinecarboxylic acid,Boc-α-(4-trifluormethylbenzyl)-D-proline

Peptide Synthesis
Serves as a specialised building block in solid-phase or solution-phase peptide synthesis to introduce a non-natural amino acid residue. The trifluoromethylbenzyl group can impart unique properties to the resulting peptide chain.
Chemical Synthesis
Utilised as an intermediate in the synthesis of complex organic molecules. The chiral nature and functional groups of this compound allow for stereoselective reactions and the construction of intricate molecular architectures.
Chemical Biology Research
Employed in the development of modified peptides or peptidomimetics for biological studies. The trifluoromethyl group can act as a label or influence pharmacokinetic properties.
| Molecular weight | 373.37 |
|---|---|
| Empirical formula | C18H22F3NO4 |
| Assay | ≥98.0% (HPLC) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH used for?
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Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH is used in chemical synthesis, peptide chemistry, and chemical biology research as a specialised building block for creating complex molecules and modified peptides.
What is the CAS number and formula for Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH?
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The CAS number is 1217720-94-9 and the empirical formula is C18H22F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH with an assay of ≥98.0% (HPLC). This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This chemical may cause long lasting harmful effects to aquatic life (H413). Wear eyeshields and gloves when handling. It is classified under WGK 2 in Germany.
How is this chemical shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures appropriate packaging and documentation for the safe shipment and export of this chemical worldwide.
How can I request a sample or quote?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a sample or a quotation for Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH.
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