Boc-1-tert-butoxy-1,2-dihydroisoquinoline
Boc-1-tert-butoxy-1,2-dihydroisoquinoline (CAS: 404586-94-3) is a chemical compound with the molecular formula C18H25NO3 and a molecular weight of 303.40 g/mol. This isoquinoline derivative functions as a versatile tert-butoxycarbonylation protecting reagent. It is primarily utilised in chemical synthesis for the protection of various acidic substrates, including phenols, amines, and carboxylic acids, facilitating complex molecular construction.
- IUPAC
- 1-tert-Butoxy-2-butoxycarbonyl-1,2-dihydroisoquinoline,BBDI
- Synonyms
- 1-tert-Butoxy-2-butoxycarbonyl-1,2-dihydroisoquinolineBBDI
Protecting Group Chemistry
Boc-1-tert-butoxy-1,2-dihydroisoquinoline serves as an effective tert-butoxycarbonylation reagent. It is used to protect functional groups such as phenols, amine hydrochlorides, carboxylic acids, and thiols during synthetic procedures.
Synthesis of Complex Molecules
Its utility extends to protecting N-protected amino acids, sulfonamides, and imides. This makes it a valuable building block in the synthesis of more complex organic molecules and pharmaceutical intermediates.
Heterocyclic Chemistry
As an isoquinoline derivative, it finds application within heterocyclic building block chemistry, enabling the introduction or modification of the isoquinoline scaffold in target compounds.
| Molecular weight | 303.40 |
|---|---|
| Empirical formula | C18H25NO3 |
| Assay | 95% |
| Application | A versatile tert-butoxycarbonylation protecting reagent for a variety of acidic substrates including phenols, amine hydrochlorides, carboxylic acids, N-protected amino acids, thiols, sulfonamides, and imides.1 |
| Melting point | 112-116 °C |
Hazard statements
- H302Harmful if swallowed
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-1-tert-butoxy-1,2-dihydroisoquinoline used for?
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Boc-1-tert-butoxy-1,2-dihydroisoquinoline is used as a tert-butoxycarbonylation protecting reagent for substrates including phenols, amine hydrochlorides, carboxylic acids, N-protected amino acids, thiols, sulfonamides, and imides.
What is the CAS number and molecular formula for Boc-1-tert-butoxy-1,2-dihydroisoquinoline?
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The CAS number is 404586-94-3, and the molecular formula is C18H25NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-1-tert-butoxy-1,2-dihydroisoquinoline with an assay of 95%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Boc-1-tert-butoxy-1,2-dihydroisoquinoline be handled?
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Boc-1-tert-butoxy-1,2-dihydroisoquinoline is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling and safety precautions.
Is Boc-1-tert-butoxy-1,2-dihydroisoquinoline available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Boc-1-tert-butoxy-1,2-dihydroisoquinoline, adhering to all necessary shipping regulations (UN 2811 6.1/PG 3).
How can I request a quote or sample?
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To request a quote or a sample of Boc-1-tert-butoxy-1,2-dihydroisoquinoline, please use the contact form on our website or contact our sales team directly.
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