Boc-Cys(Mbzl)-OH
Boc-Cys(Mbzl)-OH (CAS 61925-77-7) is an N-protected cysteine derivative featuring a 4-methylbenzyl (Mbzl) protecting group on the thiol side chain. Its linear formula is C <sub>16</sub>H<sub>23</sub>NO <sub>4</sub>S and it has a molecular weight of 325.42 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research, offering a protected form of cysteine for controlled incorporation into peptide chains. It is a key building block for creating modified peptides and proteins.
- IUPAC
- Boc-S-(4-methylbenzyl)-L-cysteine
- Synonyms
- Boc-S-(4-methylbenzyl)-L-cysteine

Peptide Synthesis
Boc-Cys(Mbzl)-OH is a crucial protected amino acid derivative for solid-phase and solution-phase peptide synthesis. The Boc and Mbzl groups allow for selective deprotection and coupling steps, enabling the controlled assembly of complex peptide sequences.
Chemical Biology
This compound serves as a valuable tool in chemical biology for the synthesis of labelled or modified peptides. The protected cysteine residue can be incorporated into biomolecules to investigate protein function, drug interactions, or biological pathways.
Organic Synthesis
As a functionalised amino acid, Boc-Cys(Mbzl)-OH is employed in various organic synthesis routes. It can be used to introduce cysteine moieties into diverse organic molecules, facilitating the development of novel compounds with specific properties.
| Molecular weight | 325.42 |
|---|---|
| Linear formula | CH3C6H4CH2SCH2CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥96.0% (HPLC) |
| Optical activity | [α]/D -34.0±3.0°, c = 2 in methanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Cys(Mbzl)-OH used for?
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Boc-Cys(Mbzl)-OH is used in peptide synthesis and chemical biology as a protected form of cysteine, allowing for controlled incorporation into peptide chains and the creation of modified peptides and proteins.
What is the CAS number and formula for Boc-Cys(Mbzl)-OH?
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The CAS number for Boc-Cys(Mbzl)-OH is 61925-77-7 and its linear formula is C <sub>16</sub>H<sub>23</sub>NO <sub>4</sub>S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Cys(Mbzl)-OH with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, or EP grade. It is suitable for research and chemical synthesis purposes.
How should Boc-Cys(Mbzl)-OH be handled safely?
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When handling Boc-Cys(Mbzl)-OH, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if there is a risk of aerosol formation. The compound has a WGK (Germany) of 3.
Is Boc-Cys(Mbzl)-OH a controlled substance?
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The provided data does not indicate that Boc-Cys(Mbzl)-OH is a controlled substance.
How is Boc-Cys(Mbzl)-OH packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details for Boc-Cys(Mbzl)-OH will be provided upon inquiry, adhering to all relevant international shipping regulations for chemical compounds.
How can I request a sample or quote for Boc-Cys(Mbzl)-OH?
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To request a sample or a quote for Boc-Cys(Mbzl)-OH, please contact our sales team through the Tech Serve Solutions website or via direct inquiry, providing your contact details and the quantity required.
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