3,3,3-Trifluoro-3-[(2-tetrahydrothienyl)methyl]propionic acid
3,3,3-Trifluoro-3-[(2-tetrahydrothienyl)methyl]propionic acid (CAS: 480438-83-3) is a specialised organic compound featuring a trifluoromethyl group and a tetrahydrothiophene moiety. With a molecular weight of 228.23 g/mol, this building block is valuable in synthetic chemistry for introducing fluorinated heterocyclic structures. Its unique combination of functional groups makes it a key intermediate for research and development in pharmaceuticals and material sciences.
- Synonyms
- 480438-83-3
![3,3,3-Trifluoro-3-[(2-tetrahydrothienyl)methyl]propionic acid (C4SH7CH2CH(CF3)COOH) — chemical structure, CAS 480438-83-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480438-83-3.png&w=3840&q=75)
Fluorinated Building Block
This compound serves as a crucial building block in organic synthesis, particularly for the introduction of trifluoromethylated heterocyclic motifs into more complex molecules. Its structure is advantageous for exploring novel fluorinated compounds in drug discovery.
Pharmaceutical Intermediates
It acts as a valuable intermediate in the synthesis of potential pharmaceutical candidates. The presence of the trifluoromethyl group can enhance metabolic stability and lipophilicity, properties often sought after in drug design.
Material Science Research
Researchers in material science may utilise this compound for developing new fluorinated materials with specific properties, leveraging the unique electronic and steric effects of the trifluoromethyl and thiophene groups.
Chemical Synthesis Reagent
As a versatile reagent, it is employed in various chemical transformations, enabling the construction of diverse molecular architectures for academic and industrial research purposes.
| Molecular weight | 228.23 |
|---|---|
| Linear formula | C4SH7CH2CH(CF3)COOH |
| Boiling point | 235 °C(lit.) |
| Density | 1.376 g/mL at 25 °C(lit.) |
| Refractive index | n20/D >1.4620(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,3-Trifluoro-3-[(2-tetrahydrothienyl)methyl]propionic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly for creating fluorinated heterocyclic structures relevant to pharmaceutical intermediates and material science research.
What is the CAS number and molecular formula for this chemical?
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The CAS number is 480438-83-3. The linear formula is C4SH7CH2CH(CF3)COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are technical/research grade and are not represented as USP, BP, EP, or other pharmacopoeial standards.
What are the primary safety and handling considerations for this compound?
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This compound requires careful handling. It is classified under WGK 2 in Germany, indicating potential hazards. Appropriate personal protective equipment, including eyeshields, gloves, and a P1 or N95 respirator filter, should be used during handling to prevent exposure.
How is this chemical typically packed and shipped by TSS?
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Tech Serve Solutions packs and ships chemicals in compliance with international shipping regulations. Specific packaging details are available upon request for export.
How can I request a quote or sample for 3,3,3-Trifluoro-3-[(2-tetrahydrothienyl)methyl]propionic acid?
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To request a quote or a sample, please contact our sales department via the website or email, providing the product name and CAS number (480438-83-3).
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