3,3,3-Trifluoropropane-1-sulfonyl chloride
3,3,3-Trifluoropropane-1-sulfonyl chloride (CAS: 845866-80-0) is an organosulfur compound with the molecular formula C3H4ClF3O2S and a molecular weight of 196.58 g/mol. This reactive sulfonyl chloride serves as a valuable building block in organic synthesis. Its applications span various chemical research and development sectors, offering a unique trifluoropropylsulfonyl moiety for incorporation into more complex molecular structures.
- Synonyms
- 845866-80-0C3H4ClF3O2S
Organic Synthesis Intermediate
This compound is a key intermediate in the synthesis of novel organic molecules. The trifluoropropylsulfonyl group can be introduced into various substrates to modify their chemical and physical properties.
Pharmaceutical Research
As a building block, it can be utilised in the development of new pharmaceutical candidates. The introduction of fluorine atoms often enhances metabolic stability and lipophilicity in drug molecules.
Material Science
The unique properties imparted by the trifluoromethyl group may find application in the development of specialized materials. Its reactivity allows for covalent attachment to polymers or surfaces.
| Molecular weight | 196.58 |
|---|---|
| Empirical formula | C3H4ClF3O2S |
| Assay | 95% |
| Boiling point | 77-78 °C/16 mmHg |
| Density | 1.557 g/mL at 25 °C |
| Refractive index | n20/D 1.3996 |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,3-Trifluoropropane-1-sulfonyl chloride used for?
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3,3,3-Trifluoropropane-1-sulfonyl chloride is primarily used as a building block in organic synthesis, particularly in the development of new pharmaceutical agents and materials due to its trifluoropropylsulfonyl moiety.
What is the CAS number and molecular formula?
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The CAS number for 3,3,3-Trifluoropropane-1-sulfonyl chloride is 845866-80-0, and its molecular formula is C3H4ClF3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3,3-Trifluoropropane-1-sulfonyl chloride with an assay of 95%. This is a technical/research grade material and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,3,3-Trifluoropropane-1-sulfonyl chloride be handled safely?
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This compound is classified as Dangerous (GHS05, Danger) and causes severe skin burns and eye damage (H314). It reacts violently with water. Always use appropriate personal protective equipment, including gloves, goggles, face shields, and suitable respiratory protection, and handle in a well-ventilated area, strictly avoiding contact with moisture.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,3,3-Trifluoropropane-1-sulfonyl chloride, adhering to all international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quote for 3,3,3-Trifluoropropane-1-sulfonyl chloride, please contact our sales team through the website or via direct inquiry.
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