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3,3,3-Trifluoro-3-[(2-tetrahydrofuranyl)methyl]propionic acid, mixture of diastereomers

CAS 480438-81-1C8H11F3O3Chemical Synthesis

3,3,3-Trifluoro-3-[(2-tetrahydrofuranyl)methyl]propionic acid, a mixture of diastereomers (CAS 480438-81-1), is a fluorinated carboxylic acid with the empirical formula C8H11F3O3 and a molecular weight of 212.17 g/mol. This heterocyclic compound serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceutical intermediates and other complex molecules. Its unique structural features make it a key intermediate for research and development in medicinal chemistry.

Synonyms
mixture of diastereomers480438-81-1C8H11F3O3
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3,3,3-Trifluoro-3-[(2-tetrahydrofuranyl)methyl]propionic acid, mixture of diastereomers (C8H11F3O3) — chemical structure, CAS 480438-81-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC8 to C11Chemical SynthesisFuransHeterocyclic Building Blocks
01 /Applications

Fluorinated Building Block

This compound is utilised as a critical building block in synthetic organic chemistry due to its trifluoromethyl and furan moieties. It enables the introduction of fluorinated groups into target molecules, which can modulate pharmacokinetic and pharmacodynamic properties.

Pharmaceutical Intermediate

It serves as an intermediate in the synthesis of complex pharmaceutical agents. The trifluoromethyl group is often incorporated to enhance metabolic stability, lipophilicity, and binding affinity of drug candidates.

Research and Development

Primarily used in R&D settings, this chemical aids chemists in exploring new synthetic routes and developing novel compounds with potential therapeutic applications.

02 /Properties
Molecular weight212.17
Empirical formulaC8H11F3O3
Assay97%
Boiling point253-254 °C(lit.)
Density1.308 g/mL at 25 °C(lit.)
Refractive indexn20/D >1.4180(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
480438-81-1
MDL number
MFCD03427206
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,3,3-Trifluoro-3-[(2-tetrahydrofuranyl)methyl]propionic acid used for?

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This compound is used as a building block in chemical synthesis, particularly for developing pharmaceutical intermediates and exploring new fluorinated molecules.

What is the CAS number and empirical formula?

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The CAS number is 480438-81-1 and the empirical formula is C8H11F3O3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical at a purity of 97%. We do not represent this product as USP, BP, or EP grade.

What are the safety precautions for handling this chemical?

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Handling requires basic safety precautions, including the use of eyeshields and gloves. Please consult the Safety Data Sheet (SDS) for comprehensive handling information and hazard details, noting its WGK Germany classification of 3.

Can Tech Serve Solutions export this chemical?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.

How can I request a sample or a quote?

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Please contact our sales team via the website to request a sample or obtain a quotation for this product.

Need 3,3,3-Trifluoro-3-[(2-tetrahydrofuranyl)methyl]propionic acid, mixture of diastereomers in a specific grade or volume?