3,3,3-Trifluoro-DL-alanine
3,3,3-Trifluoro-DL-alanine (CAS 17463-43-3), with the linear formula CF3CH(NH2)CO2H and molecular weight 143.06 g/mol, is a trifluoromethylated derivative of alanine. This unnatural amino acid is primarily utilised as a building block in chemical synthesis and peptide chemistry. Its unique trifluoromethyl group imparts distinct properties, making it valuable for creating novel compounds with altered physicochemical characteristics for research and development purposes.
- Synonyms
- 17463-43-3
Chemical Synthesis Intermediate
3,3,3-Trifluoro-DL-alanine serves as a key intermediate in the synthesis of complex organic molecules. Its incorporation allows for the introduction of a trifluoromethyl group into target structures, influencing properties like lipophilicity and metabolic stability.
Peptide and Protein Chemistry
This unnatural amino acid is employed in the design and synthesis of modified peptides and proteins. Its presence can alter peptide conformation, receptor binding affinity, and enzymatic resistance, aiding in biochemical research.
Drug Discovery and Development
The trifluoromethyl moiety is a common feature in pharmaceuticals. 3,3,3-Trifluoro-DL-alanine is used as a precursor or building block in the development of new chemical entities (NCEs) for potential therapeutic applications.
Materials Science Research
Investigating the incorporation of fluorinated amino acids into polymers or other materials can lead to novel properties. This compound can be a starting point for such advanced material research.
| Molecular weight | 143.06 |
|---|---|
| Linear formula | CF3CH(NH2)CO2H |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Melting point | 231-234 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,3-Trifluoro-DL-alanine used for?
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3,3,3-Trifluoro-DL-alanine is primarily used as a building block in chemical synthesis, peptide chemistry, and drug discovery research due to the unique properties conferred by its trifluoromethyl group.
What is the CAS number and chemical formula for 3,3,3-Trifluoro-DL-alanine?
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The CAS number is 17463-43-3, and the linear chemical formula is CF3CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3,3-Trifluoro-DL-alanine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3,3,3-Trifluoro-DL-alanine be handled?
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This compound is classified with Warning signal word and hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is 3,3,3-Trifluoro-DL-alanine shipped and exported?
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3,3,3-Trifluoro-DL-alanine is typically stored at 2-8°C. Tech Serve Solutions professionally packs and exports this chemical globally, adhering to all necessary regulations for safe transport.
How can I request a sample or quote for 3,3,3-Trifluoro-DL-alanine?
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To request a sample or a quotation for 3,3,3-Trifluoro-DL-alanine, please contact our sales team through the website or direct email.
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