3,3,3-Trifluoropropionic acid

CAS 2516-99-6CF3CH2CO2HChemical Synthesis

3,3,3-Trifluoropropionic acid (CAS: 2516-99-6), with the linear formula CF3CH2CO2H and a molecular weight of 128.05 g/mol, is a fluorinated carboxylic acid. It serves as a valuable building block in organic synthesis, particularly in the development of novel compounds and materials. Its unique trifluoromethyl group imparts specific properties, making it a reagent of interest for researchers and industrial chemists exploring new chemical entities and advanced materials.

Synonyms: 2516-99-6CF3CH2CO2H

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3,3,3-Trifluoropropionic acid (CF3CH2CO2H) — chemical structure, CAS 2516-99-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC1 to C5Carbonyl CompoundsCarboxylic AcidsChemical Synthesis

01 /Applications

Organic Synthesis Reagent

Utilised as a key intermediate or building block in the synthesis of complex organic molecules. The trifluoromethyl group it introduces can significantly alter the electronic and lipophilic properties of target compounds.

Materials Science Research

Incorporated into the development of novel polymers, liquid crystals, or other advanced materials where the presence of fluorine is desired to impart specific physical or chemical characteristics.

Pharmaceutical Intermediate

A potential precursor in the synthesis of active pharmaceutical ingredients (APIs). Fluorinated compounds are often explored in drug discovery for their metabolic stability and binding affinities.

02 /Properties

Molecular weight	128.05
Linear formula	CF3CH2CO2H
Assay	98%
Boiling point	145 °C/746 mmHg(lit.)
Density	1.45 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.333(lit.)
Melting point	9.7 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	92 °C / 197.6 °F
Transport (UN / ADR)	UN 3265 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2516-99-6

MDL number

MFCD00153292

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,3,3-Trifluoropropionic acid used for?

3,3,3-Trifluoropropionic acid is primarily used as a building block in organic synthesis, for developing novel compounds, and in materials science research. It can serve as an intermediate in the synthesis of pharmaceuticals and other fine chemicals.

What is the CAS number and formula for 3,3,3-Trifluoropropionic acid?

The CAS number for 3,3,3-Trifluoropropionic acid is 2516-99-6, and its linear formula is CF3CH2CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3,3,3-Trifluoropropionic acid with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 3,3,3-Trifluoropropionic acid be handled safely?

3,3,3-Trifluoropropionic acid is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including face shields, gloves, and respirators, is essential. Handle in a well-ventilated area.