3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid
3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid (CAS 564-10-3) is a fluorinated carboxylic acid with the linear formula (CF3)2CHCO2H and a molecular weight of 196.05 g/mol. This compound serves as a valuable building block in organic synthesis. Its highly fluorinated nature makes it useful for introducing trifluoromethyl groups in various chemical structures, particularly in research and development settings for creating novel materials or pharmaceuticals.
- Synonyms
- 564-10-3, (CF3)2CHCO2H

Fluorinated Building Block
Utilised in organic synthesis to incorporate the highly fluorinated 2-(trifluoromethyl)propionic acid moiety into larger molecules. This is crucial for developing novel compounds with altered physical and chemical properties.
Reagent in Organic Synthesis
Acts as a precursor or reagent in the synthesis of complex fluorinated organic molecules. Its unique structure can influence reaction pathways and product characteristics.
Research and Development
Employed in academic and industrial research laboratories for exploring new chemical entities and reaction methodologies. It is a key intermediate for materials science and medicinal chemistry investigations.
| Molecular weight | 196.05 |
|---|---|
| Linear formula | (CF3)2CHCO2H |
| Assay | 97% |
| Melting point | 50-53 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid used for?
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3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid is primarily used as a building block in organic synthesis, particularly for introducing fluorinated groups into molecules for research and development in areas like materials science and medicinal chemistry.
What is the CAS number and formula for 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid?
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The CAS number is 564-10-3 and the linear formula is (CF3)2CHCO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid with an assay of 97%. This product is suitable for research and technical applications, and TSS does not represent it as USP, BP, or EP grade.
How should 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid be handled?
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Based on its GHS classification (Warning, H315, H319, H335), handling requires appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust or vapours.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid.
How can I request a sample or quote?
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To request a sample or a quotation for 3,3,3-Trifluoro-2-(trifluoromethyl)propionic acid, please contact our sales team through the website or by phone.
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