4-Aminopiperidine
4-Aminopiperidine (CAS: 13035-19-3), with the molecular formula C5H10NNH2 and a molecular weight of 100.16 g/mol, is a valuable heterocyclic building block. It serves as a key reactant in the synthesis of various complex organic molecules. Its applications span diverse areas of chemical research and development, particularly in the creation of novel pharmaceutical agents and biologically active compounds.
- IUPAC
- 4-Piperidinamine,Piperidin-4-ylamine
Synthesis of Kinase Inhibitors
4-Aminopiperidine is employed as a crucial intermediate in the development of selective cyclin-dependent kinase 4/6 (CDK4/6) inhibitors and Cdk5/p25 kinase inhibitors. These compounds are significant in cancer research and therapeutic strategies.
Development of Antimalarial Agents
This chemical acts as a reactant in the synthesis of novel antimalarial compounds. The ongoing research in this area aims to find effective treatments against malaria, a persistent global health concern.
Creation of IKKβ Inhibitors
4-Aminopiperidine is utilised in the synthetic pathways leading to IKKβ inhibitors. These molecules are investigated for their potential in modulating inflammatory responses and treating related diseases.
Production of Antithrombotic Agents
It serves as a building block for orally bioavailable P2Y12 antagonists, which are designed to inhibit platelet aggregation. This application is relevant to the development of new antithrombotic therapies.
Synthesis of Soluble Epoxide Hydrolase Inhibitors
The compound is a precursor for human and murine soluble epoxide hydrolase (sEH) inhibitors. sEH inhibitors are being explored for their therapeutic potential in various conditions, including cardiovascular and inflammatory diseases.
| Molecular weight | 100.16 |
|---|---|
| Linear formula | C5H10NNH2 |
| Density | 0.945 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4910(lit.) |
| Application | Reactant for synthesis of:• Cdk5/p25 kinase inhibitors1• Antimalarials2• Selective cyclin-dependent kinase 4/6 inhibitors3• IKKβ inhibitors4• Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation5• Human and murine soluble epoxide hydrolase inhibitors6 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Grin2a(24409) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Aminopiperidine primarily used for?
+
4-Aminopiperidine (CAS: 13035-19-3) is primarily used as a reactant in the synthesis of various pharmaceutical agents, including kinase inhibitors, antimalarials, and antithrombotic compounds.
What are the CAS number and molecular formula for 4-Aminopiperidine?
+
The CAS number for 4-Aminopiperidine is 13035-19-3, and its molecular formula is C5H10NNH2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Aminopiperidine with a purity of ≥97%. We do not represent this product as USP, BP, or EP grade. For specific purity requirements, please contact our sales team.
What are the primary safety hazards associated with 4-Aminopiperidine?
+
4-Aminopiperidine is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is 4-Aminopiperidine packaged, shipped, and exported?
+
4-Aminopiperidine is carefully packaged to ensure safe transport and compliance with international shipping regulations. We have extensive experience in exporting chemicals globally.
How can I request a sample or quote for 4-Aminopiperidine?
+
To request a sample or a quote for 4-Aminopiperidine, please contact our customer service department via our website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis