4-Aminophenylboronic acid pinacol ester
4-Aminophenylboronic acid pinacol ester (CAS: 214360-73-3; Formula: C12H18BNO2; MW: 219.09) is a valuable organoboron compound supplied by Tech Serve Solutions. This chemical serves as a key reagent in sophisticated organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions. Its utility extends to the development of novel materials and probes, underpinning advancements in various scientific and industrial fields.
- IUPAC
- 2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline,4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneamine,4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylamine,4-Aminophenylboronic acid, pinacol cyclic ester
- Synonyms
- 2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneamine4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylamine4-Aminophenylboronic acid, pinacol cyclic ester
Suzuki-Miyaura Cross-Coupling Reactions
This pinacol ester is a reliable coupling partner in palladium-catalyzed Suzuki-Miyaura reactions, enabling the formation of new carbon-carbon bonds for complex molecule synthesis.
Development of Fluorogenic Indicators
It has been employed in the creation of sensitive fluorometric detection systems, such as those utilizing through-bond energy transfer for mercury(II) ion sensing.
Synthesis of Advanced Materials
Applications include the preparation of pyromellitic diimide-based polymers and oligoarylene copolymers, relevant for n-channel field-effect transistors and low band gap semiconductors.
Medicinal Chemistry Research
The compound is utilized in palladium-catalyzed Suzuki cross-couplings to synthesize novel compounds with potential antitubercular and antimicrobial properties.
| Molecular weight | 219.09 |
|---|---|
| Empirical formula | C12H18BNO2 |
| Assay | 97% |
| Application | Reagent used for• Suzuki-Miyaura cross-coupling reactions1 • Mercury(II) detection by fluorometry with new fluorogenic indicators based on through-bond energy transfer from pentaquinone to rhodamine2 • Rhodium-catalyzed amination reactions3 • Palladium-catalyzed Suzuki cross-coupling to synthesize potential antitubercular and antimicrobial compounds4 Reagent used in Preparation of • Hexaphenylbenzene derivatives as a potential bioprobe and multichannel keypad system5• Pyromellitic diimide-based polymer as matrix for solution-processable n-channel field-effect transistors6 • Alternating copolymers of oligoarylenes and naphthalene bisimides as low band gap semiconductors with electrochemical and spectroelectrochemical behavior7 • γ-secretase modulators in the treatment of Amyloid & |
| Melting point | 165-169 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Aminophenylboronic acid pinacol ester used for?
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4-Aminophenylboronic acid pinacol ester (CAS: 214360-73-3) is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions, in the development of fluorogenic indicators, and for the synthesis of advanced organic materials and potential medicinal compounds.
What are the CAS number and formula for 4-Aminophenylboronic acid pinacol ester?
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The CAS number is 214360-73-3 and the empirical formula is C12H18BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Aminophenylboronic acid pinacol ester with a minimum assay of 97%. This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 4-Aminophenylboronic acid pinacol ester be handled?
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This compound is classified as a Warning (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear a dust mask (type N95), eye shields, and gloves. Ensure adequate ventilation and avoid breathing dust. P261, P305, P351, P338 apply.
Is 4-Aminophenylboronic acid pinacol ester a controlled substance?
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Based on the provided data, there is no indication that 4-Aminophenylboronic acid pinacol ester is a controlled substance.
How is 4-Aminophenylboronic acid pinacol ester packed and shipped?
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As a global supplier, Tech Serve Solutions exports a wide range of chemicals. Specific packaging and shipping details are confirmed upon order inquiry to ensure compliance with all relevant regulations for international transit.
How can I request a sample or quote for 4-Aminophenylboronic acid pinacol ester?
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To request a sample or a quotation, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
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