3,3,3-Trifluoro-1-propyne
3,3,3-Trifluoro-1-propyne (CAS: 661-54-1) is a fluorinated alkyne with the molecular formula CF₃C≡CH and a molecular weight of 94.04 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the introduction of trifluoromethyl groups into various molecular structures. It is utilised in the development of novel pharmaceuticals, agrochemicals, and advanced materials.
- Synonyms
- 661-54-1CF3C≡CH
Organic Synthesis Reagent
3,3,3-Trifluoro-1-propyne is employed as a reagent in organic chemistry for reactions such as cycloadditions and transition-metal-catalysed couplings. Its trifluoromethyl moiety is crucial for modifying the electronic and lipophilic properties of target molecules.
Pharmaceutical Intermediate
This compound is a key intermediate in the synthesis of complex pharmaceutical agents. The incorporation of the CF₃ group can enhance drug efficacy, metabolic stability, and bioavailability.
Agrochemical Development
It finds application in the development of new agrochemicals, including herbicides and pesticides. The trifluoromethyl group often confers desirable properties such as increased potency and environmental persistence.
Materials Science
3,3,3-Trifluoro-1-propyne can be used in the synthesis of fluorinated polymers and materials with unique thermal and chemical resistance properties.
| Molecular weight | 94.04 |
|---|---|
| Linear formula | CF3C≡CH |
| Assay | 97% |
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3161 2.1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 9-16-23-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3,3-Trifluoro-1-propyne used for?
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3,3,3-Trifluoro-1-propyne is used as a reagent in organic synthesis, particularly for introducing trifluoromethyl groups into pharmaceuticals, agrochemicals, and materials.
What are the CAS number and formula for 3,3,3-Trifluoro-1-propyne?
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The CAS number is 661-54-1 and the linear formula is CF₃C≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3,3-Trifluoro-1-propyne with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety concerns when handling 3,3,3-Trifluoro-1-propyne?
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This compound is highly flammable (F, R11). Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, in a well-ventilated area. Avoid heat, sparks, and open flames.
How is 3,3,3-Trifluoro-1-propyne packed and shipped?
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3,3,3-Trifluoro-1-propyne is classified as UN 3161, Class 2.1 (flammable gas) for transport and is shipped according to international regulations for hazardous materials. Please consult our team for specific export requirements.
How can I request a sample or quote for 3,3,3-Trifluoro-1-propyne?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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