2′-Nitroacetophenone

CAS 577-59-3O2NC6H4COCH3Chemical Synthesis

2′-Nitroacetophenone (CAS: 577-59-3) is an organic compound with the molecular formula O₂NC₆H₄COCH₃ and a molecular weight of 165.15 g/mol. This ketone, featuring a nitro group ortho to the acetyl substituent, serves as a valuable building block in organic synthesis. Its chemical structure facilitates various reactions, making it a useful intermediate in the preparation of more complex molecules for research and development purposes.

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2′-Nitroacetophenone (O2NC6H4COCH3) — chemical structure, CAS 577-59-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC7 to C8Carbonyl CompoundsChemical SynthesisKetones

01 /Applications

Organic Synthesis Intermediate

2′-Nitroacetophenone is employed as a precursor in the synthesis of diverse organic compounds. Its functional groups allow for a range of chemical transformations, contributing to the development of novel molecules.

Research and Development

This compound is utilised in laboratory settings for R&D activities. It serves as a key reagent for exploring new synthetic pathways and creating custom chemical entities for various scientific investigations.

Building Block Chemistry

As a member of the ketone and carbonyl compound families, 2′-Nitroacetophenone acts as a fundamental building block. Its reactivity is exploited in multi-step syntheses across different areas of chemistry.

02 /Properties

Molecular weight	165.15
Linear formula	O2NC6H4COCH3
Assay	95%
Boiling point	159 °C/16 mmHg(lit.)
Refractive index	n20/D 1.55(lit.)
Melting point	23-27 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	112 °C / 233.6 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

577-59-3

MDL number

MFCD00007144

PubChem substance

24897892

Beilstein registry

1102322

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2′-Nitroacetophenone used for?

2′-Nitroacetophenone is primarily used as a building block and intermediate in organic synthesis and for research and development purposes in chemical laboratories.

What are the CAS number and molecular formula for 2′-Nitroacetophenone?

The CAS number for 2′-Nitroacetophenone is 577-59-3, and its linear molecular formula is O₂NC₆H₄COCH₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2′-Nitroacetophenone with an assay of 95%. We do not represent this product as USP, BP, or EP grade.

How should 2′-Nitroacetophenone be handled safely?

2′-Nitroacetophenone is classified as harmful if swallowed (H302). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection such as an ABEK respirator filter, should be used. Handle in a well-ventilated area.