D-(−)-α-Phenylglycine
D-(−)-α-Phenylglycine (CAS: 875-74-1) is an unnatural amino acid derivative with the molecular formula C8H9NO2. This chiral compound, exhibiting a specific optical rotation of [α]20/D −155°, is primarily utilised in chemical synthesis and peptide chemistry. Its distinct structure makes it a valuable building block for creating complex molecules and modified peptides, particularly within the fields of chemical biology and the development of novel phenylglycine derivatives.
- IUPAC
- (R)-(−)-2-Phenylglycine,D-2-Phenylglycine,R-(−)-α-Aminophenylacetic acid
- Synonyms
- R-(−)-2-PhenylglycineR-(−)-α-Aminophenylacetic acidD-2-Phenylglycine
Chemical Synthesis
D-(−)-α-Phenylglycine serves as a chiral building block in organic synthesis for the preparation of complex molecules and pharmaceuticals. Its structure allows for the introduction of specific stereochemistry into target compounds.
Peptide Chemistry
This unnatural amino acid is incorporated into peptide sequences to modify their properties, such as stability or biological activity. It is a key component in the synthesis of peptidomimetics and non-natural peptides.
Chemical Biology
Used as a probe or tool in chemical biology research to study biological processes or to develop new bioactive compounds. Its unique structure can be exploited to investigate protein-ligand interactions.
Derivative Synthesis
Acts as a precursor for the synthesis of various phenylglycine derivatives, which may have applications in medicinal chemistry and materials science. Research into novel derivatives is ongoing.
| Molecular weight | 151.16 |
|---|---|
| Empirical formula | C8H9NO2 |
| Assay | 99% |
| Optical activity | [α]20/D −155°, c = 1 in 1 M HCl |
| Melting point | 302 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 150 °C / 302 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-(−)-α-Phenylglycine used for?
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D-(−)-α-Phenylglycine is primarily used in chemical synthesis, peptide chemistry, and chemical biology as a chiral building block and for creating unnatural amino acid derivatives. It is also used in the synthesis of phenylglycine derivatives.
What is the CAS number and formula for D-(−)-α-Phenylglycine?
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The CAS number for D-(−)-α-Phenylglycine is 875-74-1, and its molecular formula is C8H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-(−)-α-Phenylglycine with a minimum assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should D-(−)-α-Phenylglycine be handled?
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Handling D-(−)-α-Phenylglycine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if dust is generated. Observe all safety precautions relevant to laboratory chemicals.
Is D-(−)-α-Phenylglycine a controlled substance?
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The provided data does not indicate that D-(−)-α-Phenylglycine (CAS: 875-74-1) is a controlled substance. However, users should always verify local regulations.
How is D-(−)-α-Phenylglycine packed and shipped?
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D-(−)-α-Phenylglycine is packed in compliance with safety and transport regulations. As a global supplier and exporter, Tech Serve Solutions ensures adherence to all relevant shipping standards for chemical products.
How can I request a sample or quote for D-(−)-α-Phenylglycine?
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To request a sample or a quotation for D-(−)-α-Phenylglycine, please contact the Tech Serve Solutions sales department through our website or by phone, referencing the product CAS number 875-74-1.
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