2′-Methylacetophenone
2′-Methylacetophenone (CAS: 577-16-2), with the linear formula CH₃C₆H₄COCH₃ and a molecular weight of 134.18 g/mol, is an aromatic ketone. This compound serves as a valuable building block in organic synthesis, particularly within the chemical and pharmaceutical industries. Its reactive carbonyl group and substituted aromatic ring allow for diverse chemical transformations, making it a key intermediate in the creation of more complex molecules.
- IUPAC
- 1-(2-Tolyl)ethanone,1-(2-Methylphenyl)ethanone,2-Acetyltoluene,o-Methylacetophenone,Methyl o-tolyl ketone
- Synonyms
- 1-(2-Tolyl)ethanone1-(2-Methylphenyl)ethanone2-Acetyltolueneo-MethylacetophenoneMethyl o-tolyl ketone

Organic Synthesis Intermediate
2′-Methylacetophenone is widely used as an intermediate in the synthesis of various organic compounds. Its structure is amenable to a range of reactions, including condensation, oxidation, and reduction, facilitating the construction of complex molecular architectures.
Pharmaceutical Research and Development
This compound finds application in R&D settings for the creation of novel pharmaceutical agents. It can be incorporated into synthetic routes targeting biologically active molecules, serving as a key fragment in drug discovery processes.
Specialty Chemical Production
As a C9 carbonyl compound, 2′-Methylacetophenone is employed in the manufacturing of specialty chemicals. Its utility extends to the synthesis of fine chemicals and materials where its specific structural features are required.
| Molecular weight | 134.18 |
|---|---|
| Linear formula | CH3C6H4COCH3 |
| Assay | 98% |
| Grade | purum |
| Boiling point | 214 °C(lit.) |
| Density | 1.026 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5318(lit.) |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Methylacetophenone used for?
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2′-Methylacetophenone is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and the production of specialty chemicals. It is valuable for constructing more complex organic molecules.
What are the CAS number and formula for 2′-Methylacetophenone?
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The CAS number for 2′-Methylacetophenone is 577-16-2, and its linear formula is CH₃C₆H₄COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Methylacetophenone with a purity of 98% (grade: purum). TSS does not represent this product as USP, BP, or EP grade.
How should 2′-Methylacetophenone be handled safely?
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2′-Methylacetophenone is a combustible liquid (flash point 76 °C). Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator if exposure limits are exceeded.
How is 2′-Methylacetophenone shipped and exported?
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2′-Methylacetophenone is shipped according to applicable regulations, including NA 1993 for combustible liquids, and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 2′-Methylacetophenone?
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To request a sample or quote for 2′-Methylacetophenone, please contact our sales team through the website or by phone.
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