5-Amino-2-nitrobenzoic acid
5-Amino-2-nitrobenzoic acid (CAS: 13280-60-9), with the molecular formula H₂NC₆H₃(NO₂)CO₂H and a molecular weight of 182.13 g/mol, is a fine chemical intermediate. It serves as a crucial reactant in various synthetic pathways, including the preparation of dendritic structures and biologically active compounds. Its applications span chemical biology, peptide chemistry, and the synthesis of unnatural amino acid derivatives, making it valuable for advanced research and development.
- IUPAC
- 2-Nitro-5-aminobenzoic acid,3-Carboxy-4-nitroaniline,NSC 74455
Dendritic Chain Reactions
Utilised as a reactant in two-component dendritic chain reactions, contributing to the synthesis of complex branched molecular architectures.
Enzymic Activation Studies
Employed in studies involving the enzymic activation of hydrophobic self-immolative dendrimers, furthering the understanding of biomolecular interactions.
Biologically Active Compound Synthesis
Key intermediate in the preparation of compounds such as insulin receptor tyrosine kinase activators, vital for pharmaceutical research.
Polymer-Bound Reagents
Used in the preparation of polymer-bound diazonium salts, facilitated by Merrifield resin-bound piperazine for specific synthetic applications.
| Molecular weight | 182.13 |
|---|---|
| Linear formula | H2NC6H3(NO2)CO2H |
| Assay | 97% |
| Application | Reactant for:• Two-component dendritic chain reactions1• Enzymic activation of hydrophobic self-immolative dendrimers2• Preparation of insulin receptor tyrosine kinase activator3• Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine4 |
| Melting point | 236-238 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary applications of 5-Amino-2-nitrobenzoic acid?
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5-Amino-2-nitrobenzoic acid is used as a reactant in two-component dendritic chain reactions, for the enzymic activation of hydrophobic self-immolative dendrimers, in the preparation of insulin receptor tyrosine kinase activators, and for the preparation of polymer-bound diazonium salts.
What is the CAS number and molecular formula for 5-Amino-2-nitrobenzoic acid?
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The CAS number is 13280-60-9 and the molecular formula is H₂NC₆H₃(NO₂)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-2-nitrobenzoic acid with an assay of 97%. This product is intended for research and chemical synthesis and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 5-Amino-2-nitrobenzoic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK Germany 3, indicating a high hazard to water.
Is 5-Amino-2-nitrobenzoic acid suitable for cosmetic use?
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No, this compound is intended for chemical synthesis and research applications. It is not suitable for cosmetic or personal care use. Information regarding cosmetic applications is not available in the product data.
How is this product packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping and safety regulations. Specific packaging details are available upon request.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quotation or a sample of 5-Amino-2-nitrobenzoic acid.
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