Boc-Cys(Npys)-OH
Boc-Cys(Npys)-OH (CAS 76880-29-0), chemically Nα-Boc-S-(3-nitro-2-pyridylthio)-L-cysteine, is a protected amino acid derivative with the molecular formula C13H17N3O6S2 and a molecular weight of 375.42. This compound serves as a valuable building block in peptide synthesis and related chemical research. Its structure allows for selective deprotection and modification, making it useful in various chemical biology and synthesis applications.
- IUPAC
- Nα-Boc-S-(3-nitro-2-pyridylthio)-L-cysteine
- Synonyms
- Nα-Boc-S-(3-nitro-2-pyridylthio)-L-cysteine
Peptide Synthesis
Boc-Cys(Npys)-OH is used as a protected cysteine residue in solid-phase and solution-phase peptide synthesis. The Nα-Boc group protects the amine functionality, while the S-(3-nitro-2-pyridylthio) group protects the thiol, allowing for controlled peptide chain elongation.
Chemical Biology Research
This compound finds application in chemical biology for the synthesis of modified peptides or peptidomimetics. The specific protecting groups enable targeted reactions and the study of biological processes involving cysteine-containing peptides.
Organic Synthesis Intermediate
As a functionalized amino acid, Boc-Cys(Npys)-OH acts as an intermediate in the synthesis of complex organic molecules. Its distinct protecting groups can be selectively removed under specific conditions for further chemical transformations.
| Molecular weight | 375.42 |
|---|---|
| Empirical formula | C13H17N3O6S2 |
| Assay | ≥99.0% (TLC) |
| Optical activity | [α]20/D −94±5°, c = 1% in methanol |
| Melting point | ~160 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Cys(Npys)-OH used for?
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Boc-Cys(Npys)-OH is primarily used as a protected cysteine building block in peptide synthesis and as an intermediate in chemical biology and organic synthesis research.
What is the CAS number and chemical formula for Boc-Cys(Npys)-OH?
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The CAS number for Boc-Cys(Npys)-OH is 76880-29-0, and its chemical formula is C13H17N3O6S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Cys(Npys)-OH with an assay of ≥99.0% (TLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-Cys(Npys)-OH be handled?
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Handle Boc-Cys(Npys)-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. The compound has a WGK Germany rating of 3.
Is Boc-Cys(Npys)-OH a controlled substance?
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Based on the provided data, Boc-Cys(Npys)-OH is not indicated as a controlled substance.
How is Boc-Cys(Npys)-OH shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of shipping and exporting Boc-Cys(Npys)-OH worldwide.
How can I request a sample or quote for Boc-Cys(Npys)-OH?
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Please contact the Tech Serve Solutions sales team directly via our website or listed contact information to request a sample or a quotation for Boc-Cys(Npys)-OH.
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