Boc-Cys(StBu)-OH

CAS 30044-61-2(CH3)3CSSCH2CH(COOH)NHCOOC(CH3)3Chemical Synthesis

Boc-Cys(StBu)-OH (CAS 30044-61-2) is a protected cysteine derivative with a tert-butyl disulfide group. Its linear formula is (CH3)3CSSCH2CH(COOH)NHCOOC(CH3)3 and it has a molecular weight of 309.45 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research, serving as a valuable building block for incorporating modified cysteine residues into peptides and proteins. Its protected nature facilitates controlled chain elongation.

IUPAC: Boc-S-tert-butylmercapto-L-cysteine

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Boc-Cys(StBu)-OH ((CH3)3CSSCH2CH(COOH)NHCOOC(CH3)3) — chemical structure, CAS 30044-61-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisCysteine/CystinePeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-Cys(StBu)-OH is a protected amino acid derivative essential for solid-phase and solution-phase peptide synthesis. The tert-butyldisulfide protection on the cysteine thiol group allows for selective deprotection and coupling reactions during peptide chain elongation.

Chemical Biology

This compound serves as a crucial reagent in chemical biology for modifying biomolecules. It enables the introduction of protected cysteine residues, which can be later deprotected for further conjugation or structural studies of peptides and proteins.

Chemical Synthesis

As a versatile building block in organic synthesis, Boc-Cys(StBu)-OH is used in the construction of complex molecules. Its specific protecting groups facilitate selective transformations and the creation of novel chemical entities.

02 /Properties

Molecular weight	309.45
Linear formula	(CH3)3CSSCH2CH(COOH)NHCOOC(CH3)3
Assay	≥99.0% (TLC)
Optical activity	[α]20/D −153±3°, c = 2% in methanol
Melting point	117-119 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

30044-61-2

MDL number

MFCD00084687

Beilstein registry

1982924

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Cys(StBu)-OH used for?

Boc-Cys(StBu)-OH is used as a protected amino acid derivative in peptide synthesis and chemical biology for introducing modified cysteine residues into peptides and proteins.

What is the CAS number and formula for Boc-Cys(StBu)-OH?

The CAS number is 30044-61-2. The linear formula is (CH3)3CSSCH2CH(COOH)NHCOOC(CH3)3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-Cys(StBu)-OH with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations for Boc-Cys(StBu)-OH?

Appropriate personal protective equipment, including eyeshields and gloves, is recommended. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified under WGK Germany 3.

How is Boc-Cys(StBu)-OH typically packed and shipped?

Tech Serve Solutions offers expert packing and global export services for research chemicals, ensuring product integrity and compliance with international shipping regulations.