Boc-Chg-OH
Boc-Chg-OH (CAS: 109183-71-3), also known as N-tert-butoxycarbonyl-L-alpha-cyclohexylglycine, is a protected unnatural amino acid derivative with the molecular formula C13H23NO4 and a molecular weight of 257.33 g/mol. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its unique structure allows for the introduction of non-natural residues into peptide sequences.
- IUPAC
- Boc-L-α-cyclohexylglycine
- Synonyms
- N-tert-butoxycarbonyl-L-alpha-cyclohexylglycine
Peptide Synthesis
Boc-Chg-OH is employed as a protected unnatural amino acid in solid-phase and solution-phase peptide synthesis. It enables the incorporation of cyclohexylglycine residues, altering peptide structure, stability, and biological activity.
Chemical Biology Research
This compound is used to create modified peptides for studying protein-protein interactions, enzyme mechanisms, and developing peptidomimetics. Its unnatural side chain can probe specific binding pockets or enhance resistance to proteolysis.
Drug Discovery
As a building block, Boc-Chg-OH contributes to the synthesis of novel pharmaceutical intermediates and drug candidates. Its incorporation can influence pharmacokinetic and pharmacodynamic properties of potential therapeutics.
Organic Synthesis
Beyond peptide applications, Boc-Chg-OH can be utilised in broader organic synthesis strategies where a protected cyclohexylglycine moiety is required for complex molecule construction.
| Molecular weight | 257.33 |
|---|---|
| Empirical formula | C13H23NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Chg-OH used for?
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Boc-Chg-OH is primarily used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, and drug discovery for creating modified peptides and complex organic molecules.
What are the CAS number and formula for Boc-Chg-OH?
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The CAS number for Boc-Chg-OH is 109183-71-3, and its empirical formula is C13H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Chg-OH with a purity of ≥98.0% (TLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Boc-Chg-OH?
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When handling Boc-Chg-OH, it is essential to wear safety eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a concern. The compound is classified with WGK 3 in Germany, indicating a high hazard level.
How is Boc-Chg-OH shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Boc-Chg-OH is carefully packed to ensure safe transit and exported worldwide in compliance with all relevant shipping regulations.
How can I request a quote or sample for Boc-Chg-OH?
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To request a quote or a sample of Boc-Chg-OH, please contact our sales team through the enquiry form on our website or call us directly. Our team will be pleased to assist you.
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