Acridine Orange 10-nonyl bromide
Acridine Orange 10-nonyl bromide (CAS: 75168-11-5, C26H38BrN3) is a metachromatic dye supplied by Tech Serve Solutions for fluorescence applications. With a molecular weight of 472.50, this compound serves as a lipophilic mitochondrial probe in live cells. It is instrumental in various biological research areas, including flow cytometry and microscopy, for analyzing mitochondrial function and changes during cellular processes like apoptosis.
- IUPAC
- 10-Nonylacridine orange bromide,3,6-Bis(dimethylamino)-10-nonylacridinium bromide
- Synonyms
- 10-Nonylacridine orange bromide3,6-Bis(dimethylamino)-10-nonylacridinium bromide
Mitochondrial Probe
Acridine Orange 10-nonyl bromide functions as a lipophilic probe to visualize and analyze mitochondria in living cells. Its ability to accumulate in mitochondria allows researchers to study mitochondrial dynamics and morphology.
Flow Cytometry Analysis
This dye is utilized in flow cytometry to assess mitochondrial mass and function. It aids in characterizing cellular responses, such as multidrug resistance and apoptotic changes, by enabling quantitative measurements of mitochondrial content.
Microscopy Studies
As a fluorescent probe for microscopy, Acridine Orange 10-nonyl bromide enables detailed visualization of mitochondrial networks. This application is crucial for understanding cellular structure and the impact of various treatments or conditions on mitochondria.
| Molecular weight | 472.50 |
|---|---|
| Empirical formula | C26H38BrN3 |
| Grade | for fluorescence |
| Solubility | ethanol, DMSO: soluble |
| Application | Metachromatic dye useful as a mitochondrial probe in living cells. This dye has been used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes. |
| Melting point | ≥250 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acridine Orange 10-nonyl bromide used for?
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Acridine Orange 10-nonyl bromide is used as a metachromatic dye and a lipophilic mitochondrial probe in living cells for applications in flow cytometry and microscopy. It helps analyze mitochondria, multidrug resistance, and changes in mitochondrial mass during apoptosis.
What is the CAS number and formula for Acridine Orange 10-nonyl bromide?
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The CAS number is 75168-11-5, and the empirical formula (Hill notation) is C26H38BrN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Acridine Orange 10-nonyl bromide in a grade 'for fluorescence'. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Acridine Orange 10-nonyl bromide be handled safely?
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This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation.
Is Acridine Orange 10-nonyl bromide available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Acridine Orange 10-nonyl bromide.
How can I request a sample or quote for Acridine Orange 10-nonyl bromide?
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Please contact our sales team or use the online enquiry form on our website to request a sample or a quotation for Acridine Orange 10-nonyl bromide.
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