5-(Trifluoromethyl)pyridine-3-carboxylic acid
5-(Trifluoromethyl)pyridine-3-carboxylic acid (CAS: 131747-40-5) is a heterocyclic organic compound with the molecular formula C7H4F3NO2 and a molecular weight of 191.11 g/mol. It serves as a valuable building block in organic synthesis, particularly within the chemical and pharmaceutical industries. Its trifluoromethyl pyridine structure makes it a useful intermediate for the creation of more complex molecules and active pharmaceutical ingredients.
- IUPAC
- 5-(Trifluoromethyl)nicotinic acid
- Synonyms
- 5-(Trifluoromethyl)nicotinic acid

Pharmaceutical Intermediate
This compound is employed as a key building block in the synthesis of various pharmaceutical agents. Its trifluoromethyl and pyridine functionalities allow for diverse chemical modifications to create novel drug candidates.
Agrochemical Synthesis
5-(Trifluoromethyl)pyridine-3-carboxylic acid can be utilised in the development of novel agrochemicals. The trifluoromethyl group often enhances the biological activity and stability of such compounds.
Organic Synthesis Reagent
As a functionalised pyridine derivative, it is a versatile reagent for academic and industrial research laboratories undertaking complex organic synthesis projects.
Material Science
Its unique structural features may find application in the development of specialty materials and polymers requiring specific electronic or physical properties.
| Molecular weight | 191.11 |
|---|---|
| Empirical formula | C7H4F3NO2 |
| Assay | 95% |
| Melting point | 184-189 |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)pyridine-3-carboxylic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly for pharmaceuticals and agrochemicals, due to its trifluoromethyl and pyridine moieties.
What is the CAS number and formula for 5-(Trifluoromethyl)pyridine-3-carboxylic acid?
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The CAS number is 131747-40-5, and the empirical formula is C7H4F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(Trifluoromethyl)pyridine-3-carboxylic acid with an assay of 95%. This is a technical grade product and not represented as USP, BP, or EP.
What are the safety considerations when handling 5-(Trifluoromethyl)pyridine-3-carboxylic acid?
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This compound is classified as a Warning (GHS07) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, ensuring good ventilation. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is 5-(Trifluoromethyl)pyridine-3-carboxylic acid packed and shipped?
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Products are carefully packed according to international shipping regulations and are available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of 5-(Trifluoromethyl)pyridine-3-carboxylic acid, please contact our sales team through the website or by phone.
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