5-(Trifluoromethyl)pyridine-2-thiol
5-(Trifluoromethyl)pyridine-2-thiol (CAS: 76041-72-0, Formula: C6H4F3NS) is a valuable heterocyclic building block characterised by its trifluoromethyl group and thiol functionality. With a molecular weight of 179.16 g/mol, this compound serves as a key intermediate in organic synthesis. Its primary applications lie in the development of novel pharmaceutical agents and agrochemicals, leveraging its unique structural features for targeted molecular design.
- IUPAC
- 5-(Trifluoromethyl)-2-mercaptopyridine,5-(Trifluoromethyl)-2-pyridinethiol
- Synonyms
- 5-(Trifluoromethyl)-2-mercaptopyridine5-(Trifluoromethyl)-2-pyridinethiol
Pharmaceutical Intermediate
This pyridine derivative is employed as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its trifluoromethyl and thiol groups offer versatile reaction sites for constructing complex molecular architectures relevant to drug discovery.
Agrochemical Development
The compound finds utility in the research and development of new pesticides and herbicides. Its structural motifs can be incorporated into novel agrochemical candidates to enhance efficacy and target specificity.
Organic Synthesis Reagent
As a specialised heterocyclic building block, it is used in diverse organic transformations. The presence of the electron-withdrawing trifluoromethyl group influences the reactivity of the pyridine ring and the thiol moiety.
| Molecular weight | 179.16 |
|---|---|
| Empirical formula | C6H4F3NS |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 154-159 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)pyridine-2-thiol used for?
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5-(Trifluoromethyl)pyridine-2-thiol is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical agents and agrochemicals. It serves as an intermediate in creating complex molecules with specific biological activities.
What are the CAS number and formula for 5-(Trifluoromethyl)pyridine-2-thiol?
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The CAS number for 5-(Trifluoromethyl)pyridine-2-thiol is 76041-72-0, and its molecular formula is C6H4F3NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(Trifluoromethyl)pyridine-2-thiol with an assay of 97%. This product is supplied for research and laboratory use. TSS does not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should 5-(Trifluoromethyl)pyridine-2-thiol be handled?
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Handle 5-(Trifluoromethyl)pyridine-2-thiol with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. Refer to the Safety Data Sheet for comprehensive handling information. It is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
How is this chemical shipped?
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5-(Trifluoromethyl)pyridine-2-thiol is typically stored at 2-8°C. TSS exports chemicals globally and adheres to all relevant shipping regulations for hazardous materials. Please contact us for specific shipping details.
How can I request a sample or quote?
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To request a sample or a quote for 5-(Trifluoromethyl)pyridine-2-thiol, please visit the Tech Serve Solutions website or contact our sales department directly. We aim to respond promptly to all inquiries.
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