5-(Trifluoromethyl)pyridine-3-carbonitrile
5-(Trifluoromethyl)pyridine-3-carbonitrile (CAS 951624-83-2) is a fluorinated heterocyclic compound with the molecular formula C7H3F3N2 and a molecular weight of 172.11 g/mol. As a versatile building block, it is primarily utilised in chemical synthesis and the development of novel pharmaceutical intermediates. Its structure, featuring a trifluoromethyl group and a nitrile moiety on a pyridine ring, makes it a valuable intermediate for creating complex organic molecules.
- IUPAC
- 5-(Trifluoromethyl)nicotinonitrile
- Synonyms
- 5-(Trifluoromethyl)nicotinonitrile
Pharmaceutical Intermediate Synthesis
This compound serves as a key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). The trifluoromethylpyridine scaffold is incorporated into molecules designed for various therapeutic areas.
Agrochemical Development
It can be employed in the research and development of new agrochemicals, such as herbicides or insecticides. The unique electronic properties conferred by the trifluoromethyl group can enhance biological activity.
Organic Synthesis Reagent
As a functionalized pyridine derivative, it is useful in diverse organic transformations. The nitrile group allows for further chemical modifications, expanding its utility in synthetic chemistry.
| Molecular weight | 172.11 |
|---|---|
| Empirical formula | C7H3F3N2 |
| Assay | 95% |
| Melting point | 42-46 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-37/38-41 |
| Safety statements (S) | 7/9-22-24/25-26-36/37/39-45-51 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)pyridine-3-carbonitrile used for?
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5-(Trifluoromethyl)pyridine-3-carbonitrile is primarily used as a chemical building block in organic synthesis, particularly for the development of pharmaceutical intermediates and potentially agrochemicals.
What are the CAS number and chemical formula for this compound?
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The CAS number is 951624-83-2 and the chemical formula is C7H3F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(Trifluoromethyl)pyridine-3-carbonitrile with a minimum assay of 95%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 5-(Trifluoromethyl)pyridine-3-carbonitrile be handled safely?
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This compound is classified as Dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Always handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation and avoid dust formation.
How is 5-(Trifluoromethyl)pyridine-3-carbonitrile packed and shipped?
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Tech Serve Solutions packs and exports this chemical according to international shipping regulations for hazardous materials. It is shipped under UN 2811, Class 6.1, Packing Group III.
How can I request a quote or sample?
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To request a quote or a sample of 5-(Trifluoromethyl)pyridine-3-carbonitrile, please contact our sales team through the website or by phone.
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