5-(Trifluoromethyl)pyridine-2-carboxylic acid
5-(Trifluoromethyl)pyridine-2-carboxylic acid (CAS: 80194-69-0), with the molecular formula C7H4F3NO2 and a molecular weight of 191.11 g/mol, is a vital fluorinated heterocyclic building block. This compound serves as a key intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its pyridine core functionalised with a trifluoromethyl group and a carboxylic acid moiety offers versatile reactivity for complex molecule construction.
- IUPAC
- 5-(Trifluoromethyl)picolinic acid
- Synonyms
- 5-(Trifluoromethyl)picolinic acid
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs), leveraging its unique trifluoromethylpyridine structure for drug discovery and development. Its incorporation can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Synthesis
Serves as a precursor for novel agrochemicals, including herbicides, insecticides, and fungicides. The trifluoromethyl group often enhances biological activity and environmental persistence of the final agrochemical product.
Organic Synthesis Building Block
A versatile reagent in general organic synthesis, enabling the introduction of the 5-(trifluoromethyl)pyridine motif into various organic frameworks. It is valuable for creating complex molecules with specific electronic and steric properties.
Material Science Research
Potentially utilised in the development of advanced materials where fluorinated heterocycles impart unique electronic or physical characteristics. Its structure could be integrated into functional polymers or organic electronic components.
| Molecular weight | 191.11 |
|---|---|
| Empirical formula | C7H4F3NO2 |
| Assay | 95% |
| Melting point | 133-137 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)pyridine-2-carboxylic acid used for?
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5-(Trifluoromethyl)pyridine-2-carboxylic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for 5-(Trifluoromethyl)pyridine-2-carboxylic acid?
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The CAS number is 80194-69-0 and the empirical formula is C7H4F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 95%. This is a technical/research grade material and TSS does not represent it as USP, BP, or EP grade.
How should 5-(Trifluoromethyl)pyridine-2-carboxylic acid be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (N95 type), eyeshields, and gloves. Avoid breathing dust, and ensure adequate ventilation. It is classified as an irritant to skin, eyes, and the respiratory system (H315, H319, H335).
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-(Trifluoromethyl)pyridine-2-carboxylic acid.
How can I request a sample or quote?
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Please visit the product page on the Tech Serve Solutions website to request a sample or a formal quotation. Contact details for our sales team are also available.
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