5-(Trifluoromethyl)pyridine-2-carbonyl chloride
5-(Trifluoromethyl)pyridine-2-carbonyl chloride (CAS: 128073-05-2, C7H3ClF3NO) is a halogenated heterocyclic compound with a molecular weight of 209.55 g/mol. This reactive acid chloride serves as a valuable building block in organic synthesis, particularly for introducing the 5-(trifluoromethyl)pyridine moiety into larger molecules. It is primarily utilised in research and development settings for the creation of novel chemical entities and complex organic structures.
Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of various organic molecules. Its reactive carbonyl chloride group readily participates in acylation reactions, enabling the formation of amides, esters, and other functional groups.
Pharmaceutical Research
It is employed in the development of new pharmaceutical candidates, where the trifluoromethylpyridine core can impart desirable pharmacokinetic or pharmacodynamic properties to drug molecules.
Agrochemical Development
The unique electronic properties of the trifluoromethylpyridine ring make this compound a potential building block for the synthesis of novel agrochemicals, such as herbicides or pesticides.
Materials Science
This chemical may find applications in materials science for the creation of specialised polymers or functional materials that require the incorporation of fluorinated heterocyclic structures.
| Molecular weight | 209.55 |
|---|---|
| Empirical formula | C7H3ClF3NO |
| Assay | 97% |
| Density | 1.468 g/mL at 25 °C |
| Refractive index | n20/D 1.474 |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,Xn |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)pyridine-2-carbonyl chloride used for?
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5-(Trifluoromethyl)pyridine-2-carbonyl chloride is used as a versatile building block in organic synthesis, particularly in the research and development of pharmaceuticals, agrochemicals, and novel materials.
What is the CAS number and molecular formula?
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The CAS number for 5-(Trifluoromethyl)pyridine-2-carbonyl chloride is 128073-05-2, and its molecular formula is C7H3ClF3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 5-(Trifluoromethyl)pyridine-2-carbonyl chloride be handled?
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This compound is classified as corrosive and harmful if swallowed. Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for full handling and safety information.
How is this chemical packed and exported?
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This product is shipped according to UN 3265 regulations for corrosive solids, acidic, organic, n.o.s. (contains 5-(Trifluoromethyl)pyridine-2-carbonyl chloride). TSS is an experienced global exporter of fine chemicals.
How can I request a sample or quote?
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To request a sample or obtain a quotation, please use the contact form on our website or contact our sales department directly.
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