5-(Trimethylsilyl)-4-pentyn-1-ol
5-(Trimethylsilyl)-4-pentyn-1-ol (CAS: 13224-84-5), a versatile organic building block, features a terminal alkyne protected with a trimethylsilyl group and a primary alcohol. With a molecular weight of 156.30 g/mol and empirical formula C8H16OSi, this compound is valuable in organic synthesis for introducing specific functionalities. Its structure allows for selective reactions at either the alkyne or alcohol moiety, making it a useful intermediate in the development of complex molecules and research chemicals.

Organic Synthesis
Utilised as a bifunctional building block in complex organic syntheses. The trimethylsilyl-protected alkyne allows for regioselective functionalization, while the terminal alcohol can undergo various transformations.
Chemical Research
Serves as a valuable reagent in academic and industrial research for the development of novel compounds. Its unique structure facilitates exploration in medicinal chemistry and materials science.
Intermediate in Synthesis
Acts as a key intermediate for introducing silane-protected alkynes and hydroxyl groups into target molecules. It is suitable for multi-step synthetic pathways.
| Molecular weight | 156.30 |
|---|---|
| Empirical formula | C8H16OSi |
| Assay | 96% |
| Boiling point | 76 °C/15 mmHg(lit.) |
| Density | 0.861 g/mL at 25 °C |
| Refractive index | n20/D 1.457 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trimethylsilyl)-4-pentyn-1-ol used for?
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5-(Trimethylsilyl)-4-pentyn-1-ol is primarily used as a bifunctional organic building block in chemical synthesis and research. It is valuable for introducing specific functionalities into molecules due to its protected alkyne and primary alcohol groups.
What is the CAS number and formula for 5-(Trimethylsilyl)-4-pentyn-1-ol?
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The CAS number for 5-(Trimethylsilyl)-4-pentyn-1-ol is 13224-84-5, and its empirical formula is C8H16OSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(Trimethylsilyl)-4-pentyn-1-ol with an assay of 96%. This product is suitable for research and technical applications. TSS does not represent it as USP, BP, or EP grade.
How should 5-(Trimethylsilyl)-4-pentyn-1-ol be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A half-mask respirator (EU/US) or multi-purpose combination respirator cartridge (US) is recommended. Refer to the safety data sheet for full protective measures, as it is classified under NA 1993 / PGIII with a flash point of 84 °C.
How is this chemical packed and exported?
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Tech Serve Solutions offers this chemical for domestic and international export, ensuring compliance with shipping regulations for hazardous materials like NA 1993 / PGIII.
How can I request a sample or quote for 5-(Trimethylsilyl)-4-pentyn-1-ol?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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